Equipment

Microreactor systemsBruker Avance-III 400MHz NMR spectrometerLiquid chromatography - Mass SpectrometrIRGC-MSOrganic Elemental Analysis

Micro reactor systems

Description                                              Labtrix start

Different microreactor systems are available at our research group:

Labtrix® Start (Chemtrix)
Internal volume: 1, 5 or 10 µl depending on the reactor chip used
Temperature range: -15°C to 195°C
Pressures up to 25 bar
Wetted materials: glass, PEEK, PTFE, Techtron

KiloFlow® (Chemtrix)Kiloflow
Internal volume: 13 ml
Temperature range: 10°C to 150°C
Pressures up to 20 bar
Wetted materials: glass, PEEK, ETFE, perfluoroelastomer

X-CubeTM (ThalesNano)X Cube
Temperature range: 20°C to 200°C
Pressures up to 150 bar
Wetted material: stainless steel
Compatible with gases (H2, O2, ...)
Compatible with catalyst cartridges (Pd/C, Raney Ni, ...)

Uniqsis FlowSyn
Flow rates from 5 µl/min up to 10 ml/min
Glass static mixer + Teflon 5 ml coil reactor
FlowSyn Uniqsis10 bar BPR

In house assembled microreactor
PEEK T- or Y-mixer or ETFE T-mixer
PFA-tubing (0.5 mm internal diameter)

CPC® College System
2 ml microreactor (stainless steel) + 45 ml residence time unit

Bruker Avance-III 400 MHz NMR Spectrometer equipped with BRUKER 5 mm BBFO 400 MHz Z-gradient high resolution probe

Description

State-of-the-art NMR spectrometer equipped with an observe broadband high resolution probe, fitted with an actively shielded single axis Z-gradient for 5 mm sample diameters and 400 MHz standard-bore or wide-bore magnets. The inner NMR coil can be tuned to observe 19F or any nucleus in the range from 31P to 15N. The outer NMR coil is tuned for either 1H decoupling or observation. The probe is fitted with a 2H lock channel and automatic tuning and matching (ATM).

Signal/Noise

19F sensitivity  ≥250:1  (TFT sample, with 1H decoupling)

31P sensitivity  ≥140:1  (TPP sample)

13C sensitivity  ≥160:1  (ASTM sample)

15N sensitivity  ≥20:1  (90% formamide sample)

1H sensitivity  ≥250:1  (0.1% EB sample, 2ppm noise)

Pulse Widths

19F pulse width  ≤15μs  (TFT sample)

31P pulse width  ≤15μs  (TPP sample)

13C pulse width  ≤10μs  (ASTM sample)

15N pulse width  ≤18μs  (90% formamide sample)

1H pulse width  ≤15μs  (0.1% EB sample)

Lineshape

13C spinning lineshape  ≤0.2/2/4 Hz  (50%/0.55%/0.11%, ASTM)

1H spinning lineshape  ≤0.6/6/12 Hz  (50%/0.55%/0.11%, 1% CHCl3)

Z-gradient

The probe is fitted with an actively shielded single axis Z-gradient.

Maximum gradient strength is 50 gauss/cm

Variable Temperature Range

Variable temperature range is from -150°C to +150°C*

Liquid chromatography - Mass spectrometry

Agilent 1100 LC/MSD SL - Agilent 1200 LC - 1100 Series MSD VL

HPLC : UV detection by DAD

MS : ESI -quadrole (single-quad) - electron multiplier

Agilent 1100 Prep LC

HPLC : VWD detection - fraction collector

Perkin Elmer FT-IR system

Description

PerkinElmer FT-IR system, spectrum BX with ATR (attenuated Total Reflectance) accessory (ZnSe crystal)

  • solid and liquid sampling
  • no sample preparation
  • improved sample to sample reproducibility
  • minimized user to user spectral variation

GC-MS Agilent 6890 Plus

DescriptionGC-MS

The Agilent 6890 Plus GC system is coupled to a quadropole mass selective spectrometer 5793 MSD

Gerstel CIS-4 PTV injector

Gerstel MPS2 autosampler has various introduction techniques: liquid, dynamic headspace, SPME and thermal absorption.

Organic Elemental Analysis
2400 Series II CHNS/O Elemental Analyser

Description

One analyser with three modes of operation : CHN, CHNS and Oxygen

Advanced cumbustion design for handling virtually any type of samples

Frontal chromatography for simple , reliable and accurate measurements

Automated weight entry

Analytical detector range (element range (mgs)):

  • C: 0.001 - 3.6
  • H: 0.001 - 1.0
  • N: 0.001 - 6.0
  • S: 0.001 - 2.0
  • O: 0.001 - 2.0