Clostridium-enterotoxemia: research

Enterotoxaemia is an important cause of acute mortality in milk suckling, well growing calves. The disease is very acute (death in only a few hours), which is why the calves are often found dead. The symptoms are severe colic, bloated abdomen, shock and/or bloody diarrhea. Because of the acute development, treatment is mostly impossible. The disease is caused by, among others, the alpha-toxin produced by the bacteria Clostridium perfringens. Certain feed patterns could encourage the growth and production of the toxin. Typical are the red intestines seen during autopsy and hemorrhaging and necrosis of the tips of the intestinal villi during an histological examination.

At the moment there is a study going on in the research department that has as a goal the development of an effective preventive program based on feed management, vaccination and prebiotics.

The studies in this domain led to the following Publicationspublications-PhD-thesis.