Translational Biomedical In Vivo Imaging

Target group

The target audience are beginning doctoral students in the field of pharmaceutical sciences, veterinary sciences and medical sciences that are interest in in vivo bioimaging.  This training course will give them practical information on the different in vivo imaging techniques.  Besides state-of-the-art techniques we will also show them the limitations of each technology and in vivo imaging in general.

Level

All PhD students

Organising and Scientific Committee

  • Prof Karel Deblaere (UGent, Department of Radiology and Nuclear Medicine)
  • Prof Ingeborg Goethals (UGent, Department of Radiology and Nuclear Medicine)
  • Prof Filip De Vos (UGent, Department of Pharmaceutical Analysis)
  • Prof Jimmy Saunders (UGent, Department of Veterinary medical imaging and small animal orthopaedics)
  • Prof Christian Vanhove (UGent, Department of Electronics and information systems)
  • Dr Kathelijne Peremans (UGent, Department of Veterinary medical imaging and small animal orthopaedics)
  • Dr Benedicte Descamps (UGent, Department of Electronics and information systems)
  • Prof Tony Lahoutte (VUB, Department of Nuclear Medicine)
  • Prof Marleen Verhoye (UA, Department Biomedical Sciences)

    Aim

    This training course will give practical information on the different in vivo imaging techniques. Besides state-of-the-art techniques we will also show the limitations of each technology and in vivo imaging in general. The training sessions will illustrate the lectures and offer the possibility to provide practical experience to the participants.

    Topic and theme

    In contrast to traditional biomedical imaging with microscopy, in which excised tissues are examined for histological and molecular changes, in vivo imaging distinctly provides visual and quantitative information for diverse biomedical research applications in living subjects (preclinical, veterinary and clinical). These techniques non-invasively characterize the stages and progression of diseases and eventually establish signature biomarkers. They also assess the efficacy of treatment modalities both in animal and human diseases. Additionally, in vivo imaging can characterize the metabolic changes, can analyze the ligand/target interactions and can provide structural information. In vivo imaging is performed with a range of instruments, most of which utilize a specific region of the electromagnetic spectrum. These imaging modalities include magnetic resonance imaging (MRI), X-ray computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and optical imaging (bioluminescence and fluorescence). In addition, a limited band of the sound spectrum is utilized for molecular imaging by ultrasound. A combination of different imaging
    technologies provides crucial information for the (bio)medical researcher on specific pathologies and biological changes in the living body.
    The aim of this course is to provide an overview of the available in vivo imaging modalities and their applications on three different fields: small animal imaging, veterinary sciences and clinical research applications. Besides some basic technical information, we will mainly focus on their applications. During the course many examples from own research will be presented and explained. We will also offer different demonstration sessions.

    Dates & Venue

    9 November (Mon) + 10 November (Tue) + 12 November (Thu) 2015

    UGent , Faculty Pharmaceutical Sciences, Ottergemse steenweg 460, 9000 Gent

    CONTACT INFORMATION: Ugent, Laboratory of Radiopharmacy
    Tel: + 32 (0)9 264 8045
    Fax:+ 32 (0)9 264 8071

    Flyer

    Preliminary programme

    • November 9th, 2015: MRI/fMRI

    9:00 – 9:30 Introduction to MRI Roel Van Holen
    9:30 – 10:00 preclinical animal MRI Benedicte Descamps
    10:00 – 10:30 Veterinary applications of MRI Jimmy Saunders
    10:30 – 11:00 Break
    11:00 – 11:30 Clinical applications of MRI Karel Deblaere
    11:30 – 12:00 Nanoparticles and MRI Stefaan De Smedt
    12:00 – 13:30 Lunch
    13-30 – 14:00 Introduction to fMRI Marleen Verhoye
    14:00 – 14:30 Preclinical animal fMRI Marleen Verhoye
    14:30 – 15:00 Clinical applications of fMRI Karel Deblaere
    15:00 – 15:30 Break
    15:30 - 17:30 DEMO MRI (Infinity) DEMO fMRI (Radiology UZGent)

    • November 10th, 2015: SPECT/PET

    9:00 – 9:30 Introduction to SPECT/PET Christian Vanhove
    9:30 – 10:00 Radiopharmaceuticals Filip De Vos
    10:00 – 11:00 Preclinical applications of SPECT/PET Sara Neyt, Nick Van Laeken, Julie Bolcaen
    11:00 – 11:30 Break
    11:30 – 12:30 Veterinary applications of SPECT/PET Kathelijne Peremans
    12:30 – 14:00 Lunch
    14:00 – 15:00 Clinical applications of SPECT/PET Ingeborg Goethals
    15:00 – 16:00 Immuno imaging with SPECT/PET Tony Lahoutte
    16:00 - 16:30 Break
    16:30 - 18:00 DEMO SPECT/PET (Infinity)

    • November 12th, 2015: CT/Ultrasound

    9:00 – 9:45 Introduction to CT and small animal CT Jeroen Hostens
    9:45 – 10:15 Recent development of CT in clinical applications Peter Smeets
    10:15 – 10:45 Introduction to ultrasound Abigail Swillens
    10:45 – 11:15 Veterinary application of CT and ultrasound(bubbles) Jimmy Saunders
    11:15 - 11:45 Break
    11:45 - 12:05 Introduction to bioluminescence/fluorescence imaging Christian Vanhove
    12:05 - 12:25 Clinical in vivo fluorescence imaging Giorgio Hallaert
    12:25 - 12:45 Preclinical bioluminescence imaging Olivier De Wever
    12:45 - 14:15 Lunch
    14:45 - 16:30 DEMO CT/ultrasound (veterinary sciences)

    Language

    English

    Number of participants

    Maximum 40 participants

    Evaluation criteria (doctoral training programme)

    100% presence + active participation

    Registration fee

    Free of charge for members of the Doctoral School of Life Science and Medicine and (Bioscience) Engineering of UGent, UA and VUB

    Registration

      Register here: https://webapps.ugent.be/eventManager/events/invivoimaging