Inflammatory Bowel Diseases

The Inflammatory Bowel Disease research group is focused on experimental research related to Ulcerative colitis (UC) and Crohn’s Disease (CD), together also known as inflammatory bowel disease (IBD). These are chronic relapsing diseases characterized by periods of active inflammation of the digestive tract, usually the small and/or large intestine. IBD may occur at any age but is mainly diagnosed in young adults. The symptoms include abdominal pain, vomiting, diarrhea and weight loss. To date, the cause of IBD is unknown; however a widely accepted working hypothesis is that the disease results form an overactive immune reaction towards gut micro flora in genetically susceptible hosts.

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Digestive Oncology

The Digestive Oncology research group is focused on the identification of molecular biomarkers for early detection, prediction of relapse and response to treatment of solid digestive tumors. Together these comprise esophageal, stomach, pancreas, colorectal and anal canal carcinomas.

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Hepatology

The Hepatology research group has acquired a lot of expertise in the pathophysiology of fibrosis/cirrhosis, associated portal hypertension, non-alcoholic steatohepatitis and hepatocellular carcinoma. Although the causes of hepatitis are numerous, progressive damage of the liver cells often leads to cirrhosis and associated complications.

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