International projects

PACE project: ‘Comparing the effectiveness of palliative care for elderly people in long term care facilities in Europe’

PACE (Palliative Care for Older People in care and nursing homes in Europe) pursues the following strategic scientific aims: (1) PACE will map palliative care systems in care or nursing homes in Europe; (2) PACE will perform a large-scale representative study to examine quality of dying and palliative care in care or nursing homes in Europe; and (3) PACE will study the impact of an innovative trial ‘PACE Steps to Success’ which aims to improve the quality of palliative care. More information can be consulted on www.eupace.eu 

    • Staff: Liesbeth Van Humbeeck, Let Dillen, Gwenda Albers, Marc Tanghe, Ruth Piers, Nele Van Den Noortgate
    • Collaborators: International PACE consortium under lead of Lieve Van den Block (VUB)
    • Funding: A European funded project (FP7, 2014-2019)

MID-FRAIL study: ‘A randomized clinical trial to evaluate the effectiveness of a multi-modal intervention in older people with type 2 diabetes on frailty and quality of life’

This cluster-randomised, multicentre, clinical trial aims to evaluate the effectiveness of a multi-modal intervention (education, diet and exercise), in comparison with usual clinical practice in frail and pre-frail subjects aged ≥70 years with Type 2 Diabetes. The primary outcome is any difference in function measured two years post randomisation.

    • Staff: Eline Meireson, Lore Vandaele, Stefanie De Buyser, Mirko Petrovic
    • Collaborators: Leocadio Rodríguez Mañas (Department of Geriatrics, Getafe University Hospital), Alan Sinclair (Institute of Diabetes for Older People, University of Bedforshire), Isabelle Bourdel-Marchasson (Department of Gerontology, University Hospital Centre of Bordeaux), Ivan Bautmans (Frailty in Ageing Research Department, Free University of Brussels), Antony Bayer (Section of Geriatric Medicine, Cardiff University), Juan Oliva Moreno (Economic Analysis Department, University of Castilla- La Mancha),  Giuseppe Paolisso (Department of Geriatric Medicine and Metabolic Diseases, Second University of Naples), Eva Topinkova (Department of Geriatrics, Charles University Prague), Giovanni Gambassi (Department of Geriatrics, Sacred Hearth University of Rome), Bruno Vellas (Department of Internal Medicine, University Hospital Centre of Toulouse),  Andrej Zeyfang (Institute of Epidemiology and Medical Biometry, Universityof Ulm)
    • Funding: A European funded project (FP7, 2011-2016)

International project: FP7-Health-2012 project ‘A New Software ENgine for the Assessment & optimization of drug and non-drug Therapy in Older peRsons: the SENATOR study’

This medium-scale collaborative research project aims to develop and test a highly-powered and efficient software engine (SENATOR) for the purpose of optimising the pharmacological and non- pharmacological therapy of older people with multi-morbidity.
The SENATOR software will be tested in a multi-country RCT where the primary outcomes are a reduction in non-trivial adverse drug reactions (ADRs) and care costs during acute hospital admissions. A novel tool to assess the risk of experiencing an ADR will also be developed and validated.

    • Staff: Eline Meireson, Lore Vandaele, Mirko Petrovic
    • Collaborators: Denis O’Mahony (Medicine Department, University College Cork), Roy Soiza (Division of Applied Medicine, University of Aberdeen),  Adalsteinn Gudmundsson (Department of Medicine- Geriatrics, Landspitali University Hospital Reykjavik, Iceland),  Alfonso Cruz-Jentoft (Department of Geriatrics, University Hospital Ramón y Cajal Madrid), Prof. Chakravarthi Rajkumar (Department of Geriatrics, Brighton and Sussex Medical School), Prof. Antonio Cherubini (Department of Clinical and Experimental Medicine, Univeristy of Perugia)
    • Funding: A European funded project (FP7, 2012 – 2018)