Lezing 'Engineering the immune system with synthetic nanomaterials'
Bruno De Geest, Department Pharmaceutics, UGent will present his work.
The field of immuno-engineering has vastly expanded the last decade and offers new avenues for the treatment of infectious diseases and cancer. My research group works at the interface between life sciences and materials chemistry with a special interest in polymer chemistry, nanotechnology and immunology. In my talk I will give an overview of our recent findings in how we can engineer the adaptive and innate immune system using synthetic nanomaterials to fight cancer and infectious diseases. In this regard we are developing strategies that allow for (1) efficient targeting of dendritic cells in lymphatic tissue for engineering adaptive immunity, (2) decorating cancer cells and infected cells with motifs that activate innate immunity and (3) engineering the tumor stroma.