Biomolecular engineering

Biomolecular engineering is the purposeful manipulation of biological molecules to improve their functional properties.

Following the central dogma of biochemistry, the most fundamental manipulation is done at the DNA-level (genetic engineering), which then results in improved enzymes (protein engineering) and/or specific products (metabolic engineering).

At our faculty, several groups are working on the design of molecules like specialty carbohydrates, pharmaceutical proteins and bio-active metabolites, using state-of-the-art techniques such as CRISPR-CAS and DNA-shuffling, microfluidics and high-throughput screening, in silico modeling and docking.