Clinical Pharmacology, Drug depot and Prescription

General information

Lecturers: Prof. dr. M. Devreese, Prof. dr.  P. De Backer, Prof. dr. S. Croubels; Year taught: 1st Master of Veterinary Medicine

Position of the course

The students are mainly taught the specific principles of mechanisms of action of veterinary drugs of the different classes. Special attention will be paid to the general features and key points of veterinary drugs in various animal species. Emphasis is laid on the possible therapeutic effects, indications and side effects. Furthermore, the legislation on the drugs is discussed and the correct preparation of a prescription for both food and non-food producing animals.

Contents

In the first part, the organotrope pharmaceuticals are discussed which influence the autonomic nervous system and central nervous system, hormones, cardiovascular drugs, and medicines with an influence on the renal function, respiration, eye, skin and gastrointestinal tract. In the second part the etiotrope drugs are handled. This is defined as the antiseptic, anti-infectious chemotherapeutics, antibiotics, anti-protozoal agents, antifungals, anthelmintics and ectoparasiticides. The discussion of these classes of veterinary medicines has focused on their typical mechanisms of action, indications and possible pharmacological effects in different species. Due attention is paid to aspects such as toxicity, antimicrobial resistance, rational antibiotic use, environmental impact, clinically relevant interactions, ... Following, the legislation on the drug depot and other aspects of the legislation are discussed (cascade system, residue problems, registration of medicines .. .). Finally, the various aspects of the prescription of veterinary medicinal products, for both food and non-food producing animals is discussed.

Final competences

  1. Thorough understanding of the key (patho)physiological processes on which drugs may intervene
  2. Knowledge of the mechanism of action, pharmacokinetics, indications and (side) effects of the major drug classes
  3. Knowledge of the most important drugs of each drug class and their species-specific applications
  4. Understanding the structure-activity relationship of drugs
  5. Understanding the rational use of antimicrobials in veterinary medicine
  6. Know the legislation regarding the drug depot and the purchase and provision of veterinary drugs
  7. Know and apply the cascade system and the conditions for both food and non-food producing animals
  8. Know the different registration procedures for veterinary medicines in the European Union
  9. Proper preparation of a veterinary prescription for both food and non-food producing animals, including the magisterial prescription
  10. Recognize the various forms of medicines
  11. Know and apply the control measures relating to residues of veterinary drugs in food
  12. Recognizing the economic context associated with a particular treatment of patients using generic drugs (multiperspectivism)
  13. The student can search the available formularia and select the most relevant and reliable scientific data in an informed and critical way
  14. Exhibit an ethical, professional and socially responsible behavior related to the use of veterinary drugs
  15. Convinced of and the use of life-long learning within veterinary pharmacology
  16. Implement measures to promote the sustainability of antimicrobials in veterinary medicine