Neurology: research

Prolonged duration : MMEP in horseDifferentiating subtle signs of lameness from subtle spinal cord disease may be challenging.

Research at our department developed a technique to perform Transcranial Magnetic Stimulation (TMS) or Magnetic Motoric Evoked Potentials (MMEP) as a non-invasive tool for studying spinal cord function.

  • The magnetic motor evoked potential test (MMEP-test) is a painless test performed on the standing sedated horse. A brief magnetic field trough the skull produces a motoric signal in the brains that travels through the spinal cord to the muscles in the legs.
    The impulse that arrives in the muscles is captured with a registration needle. The time lag between magnetic stimulation and capture of the stimulus in each of the legs and the amplitude of the captured signal indicate whether intact conduction through the spinal cord occurs (Fig. 1 : normal amplitude and duration).
    The conduction time will increase if the integrity of the motor nervous system is damaged (Fig. 2).
  • Electromyography (EMG) is a technique for recording the electrical activity in muscle. Muscle disorders show specific abnormalities.

Normal amplitude and duration of a MMEP-test in a horseView publications

PhD's on equine neurology