Canine mastocytoma

PhD research: Shana De VosFine needle aspirates of a mast cell tumor

Mast cell tumours are the most common skin tumour in dogs (estimated incidence of 129/100.000 dogs). In the current clinical practice, mast cell tumours are treated by surgical removal or radiotherapy.

However, 25% of Low & High grade  mast cell tumor with vWF stainingtumours metastasise and cause death within one year after diagnosis. We aim to better understand how mast cell tumours turn malignant.

This may enable us to find new therapeutic strategies to prevent metastatic disease post-surgery, but it will also help us to find better biomarkers, which will help veterinarians to decide whether adjunctive chemotherapy is advised post-surgery.

 

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