Lecture 'Regulation of the blood-brain barrier in health and neurodegenerative disease'

For whom
Students, Employees, Alumni, Business
When
01-12-2017 from 11:30 to 12:45
Where
UGent-VIB-onderzoeksgebouw, Technologiepark 927, 9052 Zwijnaarde
Language
English
Organizer
VIB-UGent Center for Inflammation Research (GE01/WE14/WE10)
Contact
coordination@irc.vib-ugent.be
Website
http://www.irc.ugent.be/index.php?id=seminars
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This talk will provide an overview of the molecular complexity of the blood brain barrier and how this barrier is regulated in health and disease.

Dr Matthew Campbell graduated from University College Dublin in 2006 with a PhD in Biochemistry followed by Post-doctoral research in Trinity College Dublin in Human Molecular Genetics (2006-2012). He has published extensively on the use of RNA interference to modulate levels of distinct tight junction proteins at the blood-brain barrier/inner blood retina barrier in vivo. Additionally, he has published numerous articles focused on understanding the molecular pathology of diseases such as age-related macular degeneration, Alzheimer's disease, Schizophrenia, traumatic brain injury and chronic traumatic encephalopathy.
This talk will provide an overview of the molecular complexity of the blood brain barrier and how this barrier is regulated in health and disease. It will present data from both basic and clinical research programs on-going in Dr Campbell's laboratory and will shed light on new potential therapeutic targets for neurodegenerative conditions such as Alzheimer's Disease.