Lecture 'How plant transport proteins convey pathogen susceptibility'

For whom
Students, Employees, Alumni, Business
When
14-11-2018 from 14:00 to 15:00
Where
UGent-VIB-onderzoeksgebouw, Technologiepark 927, 9052 Zwijnaarde
Language
English
Organizer
VIB-UGent Center for Inflammation Research (GE01/WE14/WE10)
Contact
ruth.vanlaere@ugent.be
Website
http://www.irc.ugent.be
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Prof Wolf Frommer, HH University Düsseldorf and Institute for Transformative Biomolecules ITbM, Nagoya plant transport protein vs pathogen awareness

We partially understand how assimilates are translocated from leaves into seeds. We identified transporters for cellular uptake and efflux of sugars (SUTs and the SWEETs). We found that 3 SWEET13 paralogs play a role in phloem loading in maize and identified SWEET4c as a hexose transporter in the basal endosperm transfer cell layer of maize kernels. We identified SWEET11 and 15 as key transporters during seed filling in rice. We try to establish the complete path of sugars from the site of synthesis to the storage site. We develop fluorescent biosensors for sugars and transporter activity and are exploring the regulation of the transport processes. Notably SWEETs function as pathogen susceptibility factors. Xanthomonas oryzae pv oryzae which causes leaf blight in rice uses TAL effectors to ectopically induce expression of SWEET genes. If SWEET gene induction is blocked by genome editing of effector binding sites, the resulting plants are resistant. We now explore the disease mechanism.