Lecture 'CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation'

For whom
Students, Employees, Alumni, Business
When
08-03-2019 from 11:30 to 12:45
Where
UGent-VIB-onderzoeksgebouw, Technologiepark 927, 9052 Zwijnaarde
Language
English
Organizer
VIB-UGent Center for Inflammation Research (GE01/WE14/WE10)
Contact
ruth.vanlaere@ugent.be
Website
http://www.irc.ugent.be/index.php?id-seminars
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Prof. Lienhard Schmitz, Biochemical Institute, Medical Faculty, University of Giessen (Germany)

This presentation describes the identification of a new phosphorylation event of histone H2B at serine 6 during mitosis with CDK1 and PP1 as writers and erasers of this modification. This phosphorylation contributes to chromatin dislocation of the histone chaperone SET during mitosis and is required for mitotic chromosome segregation.