Lecture 'Developmental Programming of Tissue-Resident Macrophages'

For whom
Alumni , Business , Employees , Students
When
09-12-2022 from 11:30 to 12:30
Where
UGent-VIB-onderzoeksgebouw, Technologiepark 71, 9052 Zwijnaarde
Language
English
Organizer
VIB-UGent Center for Inflammation Research
Contact
Nele.Vanlangenakker@UGent.be
Website
https://www.irc.ugent.be/index.php?id=tocalendar

This talk will discuss how macrophages can transmit the maternal obese metabolic state to the next generation.

Prof Elvira Mass (Life & Medical Sciences(LIMES) Institute, University of Bonn, Germany) is our guest speaker. More information on her talk:

The global epidemic of obesity has led to an increasing number of obese women in childbearing age. Maternal obesity may have harmful consequences on fetal and adult metabolic programming, however, the underlying mechanisms remain elusive. Macrophages have been identified as metabolite-sensing cells and important mediators of pathological conditions caused by intake of a western diet. The recent discovery that most tissue macrophages have a fetal origin places these cells in a unique position of sensing and responding to metaflammation during embryogenesis. Using a maternal obesity mouse model, we investigate how Kupffer cells contribute to the fatty liver phenotype in the offspring.

To join online, visit the website above.