Lecture 'Meet the PhD Jury: Extracellular and intracellular targeting: how to design responsive nanomedicines?'
- For whom
- Employees
- When
- 01-06-2023 from 10:30 to 13:30
- Where
- Seminar room 0.2 Gertrude Elion, Ottergemsesteenweg 460, 9000 Gent
- Language
- English
- Organizer
- Ghent Research Group on Nanomedicines, Department of Pharmaceutics
- Contact
- Katharine.Wullaert@UGent.be
Lecture invitaton by Prof Jeanne Leblond Chain, INSERM U1212 (University of Bordeaux, France)
Targeting nanomedicines to specific organs - other than the liver -, tissues or cells has raised a lot of efforts from drug delivery scientists these last years.
Significant progress has been made to better understand the biological barriers and the role of several parameters (size, surface chemistry, protein corona, …) on the fate of nanoparticles after intravenous injection.
In our group, we have focused our efforts on two biological barriers:
- the endosomal escape
- the selective binding to receptors overexpressed on the cell surface.