PhD Student

Last application date
May 23, 2022 00:00
Department
LA24 - Department of Green Chemistry and Technology
Contract
Limited duration
Degree
Master's degree in Environmental Engineering, Bioscience Engineering, Science Chemistry or equivalent. The degree requirements must be met at the start of the appointment.
Occupancy rate
100%
Vacancy type
Research staff

Job description

We welcome applications for a full-time PhD position within the Synthesis, Bioresources and Bioorganic Chemistry Research Group (SynBioC) of the Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, UGent. The PhD student will be appointed in a fellowship position on the project "TransPharm”.

A short summary of the TransPharm project:
TransPharm is an EU HORIZON 2020 project, coordinated by Ghent University in Belgium, and aims to move towards a sustainable pharmaceutical industry and to improve the European readiness for sustainable production of small molecules (active pharmaceutical ingredients, APIs) that have environmental or supply concerns. To reach the envisaged aims, the project will deliver four toolboxes for the development of greener pharmaceutical products and APIs, with the aim of analysing and predicting flow behaviour and environmental biodegradability and ecotoxicity of APIs and their synthesis pathways, identifying greener and more sustainable alternatives to pharmaceutical products / APIs of concern, reducing the footprint in synthetic schemes of APIs, and assessing the sustainability of pharmaceuticals over their entire life cycle. These toolboxes will be used to assess the potential to move towards the transition to greener pharmaceutical production. In addition, the team will elaborate on business cases for sustainable pharmaceutical products or APIs and what is needed to bring them to the market. The project will also make sure that key project results and knowledge are properly transferred towards targeted stakeholders.
Your tasks will mainly be connected to WP5 which focuses on the question how these products (API’s) can viably be developed and marketed, and how this can be encouraged. In this WP, the future of sustainable pharmaceuticals will be addressed. Regarding greener production processes, the team will describe possible ways to replace on the market existing products by products with the same active ingredient that are produced in a more environmentally friendly way.
In this WP, the synthesis of 4 ciprofloxacin derivatives will be studied. Flow synthesis will be developed for Cip-Hemi and of innovative analogues with predicted biodegradability pattern. As mitigation strategy, the innovative analogues can be prepared on smaller scale using similar batch chemistry as was used for the initial Cip-Hemi synthesis.

Job profile

Candidates are expected to have an (bio)engineering background and/or affinity with organic chemistry. For this project we are looking for someone who is critical, analytical and has a sense of initiative.
Other profile requirements:

  • You hold a Master's degree in Environmental Engineering, Bioscience Engineering, Science Chemistry or equivalent. The degree requirements must be met at the start of the appointment.
  • You are interested in scientific research in order to obtain a doctoral degree.
  • You have good writing and presentation skills.
  • You have a very good oral and written knowledge of academic English.
  • You live in Belgium or are willing to settle here for the duration of the appointment.
  • You are open to the possibility for a Joint PhD between the EU partners.

How to apply

Please send an email, no later than May 23th 2022, to:
- Prof. Dr. ir. Christian Stevens: Chris.Stevens@UGent.be
The subject of the email should contain the following title: 'Application PhD TransPharm + family name’.
The following documents must be attached: letter of motivation, CV, a copy of the highest degree and a summary of the results of the studies.
Students graduating in June 2022 are also welcome to apply.
Selection procedure:

  • Preselection based on the provided documents
  • Selection based on interviews

Planned starting date doctoral position: September 1st, 2022.
You will be recruited on the basis of competencies. Qualities of people are decisive, regardless of gender, religion, ethnic origin, age, sexual orientation or any disability.