Dr. Apr. Pieter Colin

Dr. Apr. Pieter Colin graduated as a pharmacist at Ghent University in 2008. After a 1 year period of working in the pharmaceutical industry, Pieter returned to Ghent University in 2009 to start his Ph.D. research. In 2014 he received his PhD from the same university, with a thesis entitled: “Towards model-based dose optimization of antibiotic and anti-cancer treatment regimens in specific patient populations”.

Since October 2014, he has been combining his work as an associate professor position at the department of Anesthesiology at the University Medical Center Groningen (The Netherlands) with a post-doctoral fellowship (10%) at UGent, department Bioanalysis.

Main research topics: Development and application of Bio-analytical methods in support of (clinical) pharmacology-oriented research, Translational PKPD modelling using NONMEM and (Non-linear) mixed-effects modelling in general.

At the LMBKA Pieter is currently actively involved in the following projects:
Bio-analytical method development:
•    Development of bio-analytical methods in support of future bottom-up PBPK modelling strategies to predict a.o. propofol pharmacokinetics in adults and children.
•    Enhancing the spatial resolution of our currently available tumor penetration assay through optimization of sample prep and LC-MS/MS related issues.   
(PKPD) modelling:
•    Development of a model-based individualized dosing strategy for cefepime in the intensive care unit (in collaboration with OLVZ Aalst)
•    Translational PKPD modelling in support of optimization of intraperitoneal paclitaxel therapy in patients with peritoneal carcinomatosis

Dr. Apr. Pieter Colin

Publications


Laboratory of Medical Biochemistry and Clinical Analysis, Department of Bioanalysis
Campus Heymans
Ghent University
Ottergemsesteenweg 460
B-9000 Ghent
BELGIUM
Tel.: + 32 (0)9 264 81 14
Fax: + 32 (0)9 264 81 97
E-mail: Pieter Colin

Department of Anesthesiology, University Medical Center Groningen
Hanzeplein 1, Postbus 30 001, 9700 RB Groningen, The Netherlands
Tel.: + 31 50 36 15215
E-mail: P.J.Colin@umcg.nl