Sangram Keshari Samal

Sangram Keshari Samal


Sangram Keshari Samal
Laboratory for General Biochemistry and Physical Pharmacy
Ghent University
Ottergemsesteenweg 460
9000 Gent
Tel: 0032 9 264 8047 (secretary)
Tel: 0032 9 264 808360 (direct)
Fax: 0032 9 264 8189



Sangram Keshari Samal received his PhD degree in “Biomaterials” from the School of Biomolecular Science, University of Pisa, Italy in 2009. His PhD research performed at BIOlabs, University of Pisa, Italy under the supervision of Prof. Emo Chiellini and Prof. David L. Kaplan. During his PhD, he was a visiting fellow at BWH, HST-MIT and Tufts University, USA. He undertook post-doctoral research on magnetic biomaterials for bone regeneration at Consiglio Nazionale delle Ricerche, Bologna, Italy and at Department of Organic Chemistry, University of Ghent, Belgium. He is currently pursuing his research at Laboratory of General Biochemistry & Physical Pharmacy, Department of Pharmaceutical Science, University Ghent, Belgium. His research interest is mainly focused on functionalization of polymers, designing of nano-biomaterials, cell therapy, vapor nanobubbles and bioimaging for various therapeutic applications. He has published several research articles, patents, book chapters and recently edited a book.

Summary of Research Project(s)

1. COMPACT project
This research involves the study on stability and release efficacy of different drug delivery systems in extracellular medium by FCS and SPT analysis.

2. Responsive nanocarriers for targeted controlled delivery and bioimaging applications.
The research involves designing of responsive nanocarriers conjugated with drug or other biomolecule for cellular uptake and release. In addition, injected systems are being developed by using silk protein or other thermoresponsive polymers. The injectable system will be utilized to transport the nanocarrier loaded drug to the targeted site and control the release via laser pulse or by degradation of polymer backbone.

3. Phage therapy for wound healing applications
Nanocarriers functionalized with phage is being utilized to explore the antibacterial potential for wound therapy.

4. Labeling of live cells via vapor nanobubbles for bioimaging applications
Development of new methods for cellular delivery and site specific targeting of organic fluorophores to living cells by using vapor nanobubbles.

5. Functionalized nanographene for controlled targeted delivery and bioimaging
Nanographene functionalized with hydrophobic aromatic drugs and organic fluorophores for controlled targeted delivery and bioimaging applications.