Contract work

The Laboratory of Pharmaceutical Technology offers the following scientific services :

  • formulation of dosage forms (tablets, granules, solutions, suspensions, emulsions, creams, freeze-dried products, …), including production at lab-scale using the following techniques : granulation (low- en high-shear), compression, extrusion-sferonisation, hot-stage extrusion, coating (fluid-bed), freeze-drying, …
  • characterisation of solid dosage forms (powders, granules, tablets, pellets) :
    - in-vitro dissolution (USP methods 1, 2 and 3)
    - hardness, friability and disintegration time of tablets (Eur. Pharm.)
    - compression properties of drugs and excipients (using an excentric press and compaction simulator)
    - bioadhesion test of tablets
  • physical characterization of materials
    - flow properties of powders and granules (Eur. Pharm.)
    - particle size distribution (sieve analysis and laserdiffraction)
    - thermal analysis (Differential Scanning Calorimetry)
    - water content (IR-oven, Karl Fischer titration)
    - viscosity
    - pH-determination
    - bulk and tapped volume
    - true density (He-pycnometry)
    - pore size distribution (Hg-porosimetry)
  • development and optimalisation of freeze-drying cycles
  • steam sterilisation

For more information :

Prof. Dr. Chris Vervaet
Phone : +32 (0)92648069