Intra-adipose sex steroid metabolism in relation to obesity and insulin sensitivity


J. Ruige, J.M. Kaufman

Scientific collaborators
B. Lapauw, V. Bogaert, G. Vanbillemont

Intra-adipose sex steroid metabolism and expression of key molecular markers of fat metabolism in relation to insulin sensitivity are being investigated in a population of morbid obese subjects prior to and after gastric bypass surgery.

The effects of aromatase-inhibition on insulin sensitivity (Clamp-studies) and intra-adipose expression of selected signalling molecules in fat and glucose metabolism are being investigated in a population of healthy males.


Dept. of gastro-intestinal surgery: prof. P. Pattyn en prof. Y. Van Nieuwenhove