EV-TRACK

EV-TRACKExtracellular vesicle (EV) research needs transparent reporting to facilitate interpretation and replication of experiments. To achieve this, we developed EV-TRACK, a crowdsourcing knowledgebase that centralizes EV biology and methodology with the goal of stimulating authors, reviewers, editors and funders to put experimental guidelines into practice. EV-TRACK data mining identified missing controls and inadequate reporting of experimental parameters, which we summarized into the EV-METRIC to measure transparent reporting of isolation and characterization methods. This metric represents a checklist to assess the completeness of reporting of generic and method-specific information necessary to interpret and reproduce the experiment. The overall goal of EV-TRACK is to create a transparency label that is straightforward to be interpreted and that improves reproducibility in research.