Expertise

MSsmall Expertise Centre has a broad expertise in mass spectrometry analysis of small organic molecules on a variety of biofluids, tissue extracts from plant and animal sources, extracts from microbial cultures, pharmaceuticals, foodstuffs, environmental matrices, etc. By identifying particular molecules present in these samples and determining their amounts, we can provide an insight into the underlying environmental/biological process involved in their production and occurrence.

Applications

Our expertise and areas of collaboration include a wide range of small molecule applications such as:

Plant secondary metabolite profiling
Pharmacokinetic, bioavailability and safety studies of drugs
Oxidative stability studies of food components
Mycotoxin analysis, Fungal secondary metabolite profiling
Quality control and analytics of medicines
Analysis of emerging organic micro-pollutants in the (aquatic) environment
Targeted and non-targeted analysis of organic solutes in complex matrices
Pesticide residue analysis in crop and foodstuff and environmental samples
Therapeutic drug monitoring, toxicology, clinical analysis and plant biofortification
Analysis of endogenous and xenobiotic (drug) substances in biological matrices (serum, urine, (tumor) tissue)
Detection of doping substances and their metabolites in biological fluids
Analysis of volatile organic compounds with biological effects
Metabolomics and lipidomics studies (e.g. treated versus untreated)
Bioanalysis of therapeutic and recreational drugs and metabolites in blood, plasma, urine, oral fluids, hair, exhaled breath
Profiling and identification of impurities and degradants

More information

For your inquiries about potential collaborations and our services, please contact José Diana Di Mavungu.
Find out more about our expertise per research group.