Toxoplasma gondii infection kinetics and immune responses following infection and vaccination

Promovendus/a
Rahman Mizanur
Faculteit
Faculteit Diergeneeskunde
Vakgroep
Vakgroep Virologie, Parasitologie en Immunologie
Curriculum
Md. Mizanur Rahman was born on 12th June, 1979 in Bogra, Bangladesh. In 2004, he obtained an B. Pharm in Pharmacy degree from the University of Rajshahi, Bangladesh, where he worked for six years as a Senior Executive, Product Management Department in Navana Pharmaceuticals Ltd., Bangladesh. For the upgradation of his career, in academic year 2012-2014, he followed the Interuniversity program of Molecular Biology (IPMB), a master program sponsored by VLIR-UOS of Belgium and organized by the Free University of Brussels (VUB), the Katholieke Universiteit Leuven and the University of Antwerp (UAntwerp). During his master training, Mizanur did his thesis in the Lab of Immunology, Faculty of Veterinary Medicine, University of Ghent where he was inspired by the Toxosafe project, funded by Federal Public Service for Health, Food Chain Safety and Environment (grants RF 09/6213). He continued his 3.5 years PhD study on this project, focusing on Toxoplasma gondii infection kinetics and immune responses following infection and vaccination in pigs. Mizanur Rahman is the author and coauthor of several publications in peer-reviewed international journals and participated in several international conferences with oral or poster presentations.
Academische graad
Doctor in de diergeneeskundige wetenschappen
Taal proefschrift
Engels
Promotor(en)
Prof. dr. Eric Cox - Dr. Bert Devriendt
Examencommissie
Prof. Dr. Dominiek Maes, UGent - Prof. Dr. Sarah Gabriël, UGent - Prof. Dr. Peter Geldhof, UGent - Prof. Dr. Daisy Vanrompay, UGent - Dr. Malgorzata Jennes, BD Benelux N.V., Belgium

Korte beschrijving

Toxoplasma gondii is an obligate intracellular parasite which often causes toxoplasmosis in humans and animals. It is estimated that about one third of the world population has undergone a Toxoplasma infection. Although most T. gondii infections are asymptomatic, it is a significant cause of fetal and neonatal mortality. T. gondii are highly infectious and most infections in humans are due to the consumption of raw or undercooked meat products contaminated with tissue cysts. T. gondii contaminated pork was estimated to account for 12- 15% of human toxoplasmosis. However, there is a huge knowledge gap on the host immune response and the intervention strategies. As such, to generate sufficient data to bridge some of the knowledge gaps, this PhD thesis focused on T. gondii infection kinetics and immune responses and evaluated vaccine candidates in pigs.

Praktisch

Wanneer
Dinsdag 25 februari 2020, 17:00
Waar
Auditorium Hoogbouw, Salisburylaan 133, 9820 Merelbeke