Investigations into potential alternatives for sustainable control of psoroptic mange in Belgian Blue cattle

Chen, Zhenzhen
Faculteit Diergeneeskunde
Vakgroep Virologie, Parasitologie en Immunologie
Zhenzhen Chen was born in Henan Province, China, on March 13th, 1989. In September 2009, he was admitted to Sichuan Agricultural University in China, and majored in Pharmacology in the department of Veterinary Medicine. In June 2013, he obtained his Bachelor of Science degree. In the same year, he was attained a qualification of exemptions and enrolled as a master student in Sichuan Agricultural University, where he was focused on the mode of action of Octadecanoic acid-3, 4-tetrahydrofuran diester against Sarcoptes scabiei in rabbits by a combination of transcriptomics and proteomics. At the same time, he was responsible for clinical studies on a new antiparasitic drug. Furthermore, he obtained one invention patent with his MSc supervisor. After graduation in 2016, he received a PhD scholarship from the Chinese Scholarship Council, to start his PhD research at the Laboratory of Parasitology, Faculty of Veterinary Medicine, Ghent University. His PhD research focused on potential alternatives for sustainable control of psoroptic mange in Belgian Blue cattle. During his PhD, he successfully completed the Doctoral Training Programme, organized by the Ghent University Doctoral Schools. He is author/co-author of ten scientific publications in national and international journals. He has given four oral/poster presentations in national and international scientific conferences/symposia.
Academische graad
Doctor in de diergeneeskundige wetenschappen
Taal proefschrift
Prof. dr. Edwin Claerebout, Faculty of Veterinary Medicine, UGent - Prof. dr. Peter Geldhof, Faculty of Veterinary Medicine, UGent
Prof. dr. Luc Duchateau, Chairman of the Examination Board, UGent - Prof. dr. Stewart Burgess, Moredun Research Institute, Pentlands Science Park, UK - Prof. dr. Bertrand Losson, Faculty of Veterinary Medicine, University of Liège - Prof. dr. Geert Opsomer, Faculty of Veterinary Medicine, UGent - Prof. dr. Bert Devriendt, Faculty of Veterinary Medicine, UGent

Korte beschrijving

Psoroptes ovis, the causative agent of psoroptic mange, causes severe allergic dermatitis and intense pruritus in sheep and cattle. The disease is highly contagious and causes impaired animal welfare and economic losses in livestock all over the world. In cattle, psoroptic mange is a severe problem, especially in Belgian Blue (BB) beef farms. The BB cattle breed is highly susceptible to P. ovis infestation, whilst other breeds such as Holstein Friesian (HF) seem to be more resistant. The reason for this difference has not been clarified yet, but could be caused by host factors, such as genetic and immunologic variations. Although currently available treatments still work to some degree, psoroptic mange is increasingly difficult to treat, due to the development of acaricide resistance. Therefore, alternative control measures should be investigated.


Donderdag 25 februari 2021, 16:30
Diergeneeskunde, Salisburylaan 133, 9820 Merelbeke

The defense takes place on Thursday 25 February 2021 at 16h30. The defence will be in English. Due to current Covid-19 measures, the defence will only be accessible online. If you wish to attend, please register by sending an email to before 24 February 2021 to receive a personal invitation.