Protein Technologies

Overview of the technologies UGent and VIB are developing to support and enhance biopharmaceutical development.

Recombinant protein production

  • Engineering of eukaryotic protein expression systems (Pichia pastoris, HEK293, CHO)
  • Glyco-engineering of recombinant proteins in eukaryotic expression systems
  • VersaTile platform: modular synthesis of (neo)functionalized biomolecules

Proteomics

    • ProteoGent – Intact protein analysis & mass spectrometry service center
    • Differential & PTM-based proteomics
    • Advanced proteomics analysis software tool: IONBOTTM
    • Tissue Leakage Protein (TLP) enrichment for biomarker discovery
    • Glycosylation analytics

Protein interaction studies

  • Virotrap technology 
  • CRISPR/Cas9-enabled affinity purification
  • Thermal profiling

Structural protein biology

    Fully integrated structural characterization of biomolecules and the functional complexes they reside in

Nanodelivery technology development

  • Focused around degradable (bio)polymers for active compound delivery in application fields such as immuno-oncology