Protein Technologies
Overview of the technologies UGent and VIB are developing to support and enhance biopharmaceutical development.
Recombinant protein production
- Engineering of eukaryotic protein expression systems (Pichia pastoris, HEK293, CHO)
- Glyco-engineering of recombinant proteins in eukaryotic expression systems
- VersaTile platform: modular synthesis of (neo)functionalized biomolecules
Proteomics
- ProteoGent – Intact protein analysis & mass spectrometry service center
- Differential & PTM-based proteomics
- Advanced proteomics analysis software tool: IONBOTTM
- Tissue Leakage Protein (TLP) enrichment for biomarker discovery
- Glycosylation analytics
Protein interaction studies
- Virotrap technology
- CRISPR/Cas9-enabled affinity purification
- Thermal profiling
Structural protein biology
Fully integrated structural characterization of biomolecules and the functional complexes they reside in
Nanodelivery technology development
- Focused around degradable (bio)polymers for active compound delivery in application fields such as immuno-oncology