Recent Publications

2014

• Precisely and accurately localizing single emitters in fluorescence microscopy. Nature Methods 11, 253-266 (2014).

Deschout H., Cella Zanacchi F., Mlodzianoski M., Diaspro A., Bewersdorf J., Hess S.T., Braeckmans K.

• Understanding ultrasound induced sonoporation: Definitions and underlying mechanisms. Advanced Drug Delivery. Reviews. In press. (2014)

Lentacker I., De Cock I., Deckers R., De Smedt S.C., Moonen C.T.W.

2013

• On-chip light sheet illumination enables diagnostic size and concentration measurements of membrane vesicles in biofluids. Nanoscale 6, 1741-1747 (2013).

Deschout H., Raemdonck K., Stremersch S., Maoddi P., Mernier G., Renaud P., Jiguet S., Hendrix A., Bracke M., Van den Broecke R., Röding M., Rudemo M., Demeester J., De Smedt S.C., Strubbe F., Neyts K., Braeckmans K.

2012

• Cytotoxic Effects of Gold Nanoparticles: A Multiparametric Study. ACS Nano 6, 5767-5783 (2012).

Soenen S.J., Manshian B., Montenegro J.M., Amin F., Meermann B., Thiron T., Cornelissen M., Vanhaecke F., Doak S., Parak W.J., De Smedt S., Braeckmans K.

• Crucial factors and emerging concepts in ultrasound triggered drug delivery. Journal of Controlled Release. 164(3), 248-255. (2012)

Geers B., Dewitte H., De Smedt S.C., Lentacker I.

2011

• Dynamic Colocalization Microscopy to Characterize Intracellular Trafficking of Nanomedicines. ACS Nano 5, 7874-7884 (2011).

Vercauteren D., Deschout H., Remaut K., Engbersen J.F.J., Jones A.T., Demeester J., De Smedt S.C., Braeckmans K.

• Cellular toxicity of inorganic nanoparticles: common aspects and guidelines for improved nanotoxicity evaluation. Nano Today 6, 446-465 (2011).

Soenen S., P. Rivera-Gil, Montenegro J.M., Parak W., De Smedt S.C., Braeckmans K.

• Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes. Biomaterials 32, 3072-3084 (2011).

Vercauteren  D., Piest M., van der Aa L.J., Al Soraj M., Jones A.T., Engbersen J.F.J., De Smedt S.C., Braeckmans K.

• mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells. Biomaterials. 32(34) 9128-9135. (2011)

De Temmerman Marie-Luce, Dewitte Heleen, De Smedt Stefaan, Lentacker I.1, Rejman J.1

2010

• Sizing nanomatter in biological fluids by fluorescence Single Particle Tracking. Nano Letters 10, 4435-4442 (2010).

Braeckmans K., Buyens K., Bouquet W., Vervaet C., Joye P., De Vos F., Plawinski L., Doeuvre L., Angles-Cano E., Sanders N.N., Demeester J., De Smedt S.C.

• The use of inhibitors to study endocytic pathways of gene carriers: Optimisation and pitfalls. Mol. Ther. 18, 561-569 (2010).

Vercauteren D., Vandenbroucke R.E., Jones A.T., Rejman J., Demeester J., De Smedt S.C., Sanders N.N., Braeckmans K.

• Design and evaluation of doxorubicin containing microbubbles for ultrasound triggered doxorubicin delivery. Molecular Therapy. 18(1), 101-8. (2010)

Lentacker I., Geers B., Demeester J., De Smedt S.C., Sanders N.N.

2009

• Drug loaded microbubble design for ultrasound triggered delivery. Soft Matter, 5(11), 2161-2170. (2009)

Lentacker I., De Smedt S.C., Sanders N.N.

2007

• Lipoplex-loaded microbubbles for gene delivery: a Trojan horse controlled by ultrasound. Advanced Functional Materials 17(12) 1910-1916. (2007)

Lentacker I., De Smedt S.C., Demeester J., Sanders N.N.

2003

• Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope. Biophys. J. 85, 2240-2252 (2003).

Braeckmans K., Peeters L., Sanders N.N., De Smedt S.C., and Demeester J.

• Encoding microcarriers by spatial selective photobleaching. Nat. Mater. 2, 169-173 (2003).

Braeckmans K., De Smedt S.C., Roelant C., Leblans M., Pauwels R., and Demeester J.

2002

• Encoding microcarriers: Present and future technologies. Nat. Rev. Drug Discov. 1, 447-456 (2002).

Braeckmans K., De Smedt S.C., Leblans M., Pauwels R., and Demeester J.