Defended Ph. D. theses

Name date Title

Cedrine de Backere

23.08.2022 Impact of lubrication on process and tablet quality in a direct compression process

Joris Lammens


Development and characterisation of a continuous freeze drying technology for unit doses

Aseel Samaro


Innovative applications of hot-melt extrusion and additive manufacturing for the development of oral solid dosage forms

Bram Bekaert 16.12.2021

Continuous direct compression : improved process knowledge about the feeding and blending unit operation

Lise Vandevivere 09.11.2021

The impact of binders on formulation design in a continuous pharmaceutical manufacturing process based on twin screw wet granulation

Christoph Portier 26.10.2021

Improved process and formulation understanding during continuous twin screw wet granulation and downstream processing

Elien De Coninck 20.02.2020 Prilling of API-fatty acid suspensions: an innovative pharmaceutical production technique for multiparticulate dosage forms
Simon Van Herck 20.05.2019 Interactive polymers for innate immune activation
Kaat De Clercq 23.04.2019 Development of paclitaxel-loaded gelatin microspheres with a dual application for the treatment of advanced ovarian cancer: prevention of postsurgical peritoneal adhesions and recurrence of peritoneal carcinomatosis
Ruben De Coen 07.02.2019 Synthetic carbohydrate biomaterials for innate immune-engineering
Bernd Van Snick 13.03.2019 Experimental and model-based analysis of a continuous direct compression platform for oral solid dosage manufacturing
Wouter Grymonpré 01.10.2018 Increasing pharmaceutical process understanding for twin-screw extrusion and tablet manufacturing
Hui Li 17.05.2018 High-aspect-ratio nano-materials for biomedical applications
Glenn Verstraete 20.02.2018

Thermoplastic polyurethanes for the manufacturing of high drug loaded sustained release matrices

Benoit Louage 16.03.2017

Design, synthesis and evaluation of advanced polymeric taxane formulations

Lien Lybaert 11.01.2017

Design of immune-modulating polymeric microparticles in view of cell-derived cancer vaccination

Nane Vanparijs 06.10.2016 Design of protei-reactive polymers and core-crosslinked nanoparticles in view of vaccine delivery
Valérie Vanhoorne 23.08.2016 Towards continuous pharmaceutical tablet manufacturing: implementation of continuous agglomeration techniques
Wesley De Jaeghere 26.05.2016 Partially hydrolyzed polyvinyl alcohol as functional excipient in oral solid dosage forms prepared via extrusion
Zhiyue Zhang 19.05.2016 Interactive RAFT polymer-decorated gold nanoparticles for biomedical use
Anouk Vervaeck 08.09.2015 Prilling of fatty acids as innovative technology for oral controlled release multiple-unit systems
Ann-Katrien Vynckier 14.06.2015 Co-extrusion as a continuous production process for fixed-dose combination dosage forms
Bart Claeys 31.03.2015 Non-conventional polymers as matrix excipients for hot melt extruded oral-release formulations
Jurgen Vercruysse 17.11.2014 Innovation in pharmaceutical manufacturing of solid dosage forms via continuous wet granulation
Elisabeth Peeters 07.11.2014 Investigation of the tableting process in continuous production : influence of feeding and extended dwell time during compression on dependent process variables and tablet properties
Lien Dierickx 01.10.2014 Hot-melt co-extrusion as manufacturing technique for multilayer oral dosage forms
Marijke Dierendonck 07.07.2014 Nanoporous microparticles : towards a generic vaccine formulation platform
Margot Fonteyne 07.03.2014 Development and validation of process analytical methods for a continuous pharmaceutical manufacturing process of tablets based on wet granulation
Lieselotte De Smet 13.12.2013 Treatment of peritoneal carcinomatosis via (hyperthermic) intraperitoneal chemotherapy : towards a unified standard of care
Lien Saerens 18.11.2013 Spectroscopic process monitoring for quality assessment, visualization and understanding of pharmaceutical hot-melt extrusion
Joke Lenoir 12.04.2013 Development and optimization of a screening method for clinical discomfort using the Slug Mucosal Irritation test
Samata Mehta 16.01.2013 Multiparticulates for vaginal drug delivery
Andre Antunes 18.12.2012 Development and evaluation of solvent-free processing techniques for poorly water soluble drugs
Anneleen Burggraeve 19.09.2012 Development of process analytical and control methodologies for pharmaceutical wet granulation processes
Katrien Huyghe 09.04.2012 Dry powder vaccines for mass vaccination of poultry : new formulations, comparison with liquid vaccines and feasibility to decrease adverse vaccinal reactions
Liesbeth De Cock 14.11.2011 Design of growth factor-loaded tissue engineering scaffolds full-text available dissertation
Matthieu Ravelingien 16.09.2010 Development of titanium bone scaffolds with drug delivery system
Charlotte Verrue 08.06.2010 Optimisation of medication use in nursing homes: the role of the pharmacist
Katrien Vandamme 06.05.2010 Development of GantrezR AN nanoparticles for oral delivery of antigens
Egide Kayitare 26.04.2010 Development of solid paediatric oral dosage forms
Delphine Coucke 22.06.2009 Development of a platform for nasal delivery of peptides and vaccines using powder carriers based on starch
Wim Bouquet-Geerardyn 28.05.2009 Drug delivery of paclitaxel for an intraperitoneal chemotherapy in a ratmodel with peritoneal carninomatosis
Nele Poelvoorde 29.04.2009 Development of a multi-particulate formulation of viable bacteria for oral and vaginal delivery
Barbara Van Melkebeke 27.04.2009 Development and evaluation of a continuous granulation technique using a twin-screw extruder
An Cosijns 12.03.2009 Development of porous delivery systems for oral drug and vaccine administration
Ellen Verhoeven 15.12.2008 Hot-melt extrusion as processing technique for multiparticulate dosage forms containing lipophilic and hydrophilic polymers
Aleksandra Dukic-Ott 28.02.2008 Modified starch as an excipient for pellets prepared by means of extrusion and spheronisation
Yves Gonnissen 10.01.2008 Coprocessing via spray drying as a formulation platform to improve the compactability of various drugs
Pierre Claver Kayumba 04.12.2007 Taste-masked quinine formulations for flexible pediatric drug dosing in oral treatment of malaria
Evy Corbanie 03.07.2007 Development of a dry powder vaccine for mass vaccination of poultry
Eveline Pringels 08.02.2006 Nasal delivery of peptides using powder carriers based on starch/poly(acrylic acid)
Marijke Dhondt 26.10.2005 Optimisation and validation of an alternative mucosal irritation test
Nathalie Huyghebaert 21.12.2004 Development of an oral formulation of viable recombinant Lactococcus lactis and F4 fimbriae
Els Mehuys 20.12.2004 Development of a matrix-in-cylinder system for sustained zero-order drug release
Ann Debunne 06.07.2004 Development of a multiparticulate drug formulation for the administration of piroxicam to dogs
Geert Vergote 22.06.2004 Paraffinic wax beads as sustained release matrices and as cushioning agents during the compression
Eseldin Keleb 28.06.2004 Continuous agglomeration processes using a twin screw extruder
Dieter Ameye 04.03.2004 Multifunctional polymers for oral peptide and bioadhesive drug delivery
Peter Gasper Risha 04.07.2003 Quality of essential drugs on the Tanzanian market: influence of tropical climate on in vitro dissolution and bioavailability
Caroline De Brabander 13.01.2003 Development of sustained release multiple unit dosage forms using hot-melt extrusion
Brenda Vermeulen 29.11.2002 Oral bioavailability of ibuprofen enantiomers in broiler chickens and its influence on coccidiosis
Catherine Callens 28.06.2002 Ontwikkeling van een platform voor de nasale toediening van peptiden
Faustin Ndindayino 08.03.2002 Isomalt comme excipient dans la fabrication des comprimés
Dominiek Henrist 02.07.2001 Hot stage extrusion for the production of starch matrices for the oral controlled delivery of drugs
Els Adriaens 08.05.2000 Development of an alternative mucosal irritation test
Filip Kiekens 06.04.2000 Evaluation of the substrate-binder interactions in model and real granulate systems
An Vermeire 17.12.1998 Stability and compatibility of morphine and plasma levels of morphine during infusion in terminally ill patients
Sabine Inghelbrecht 26.10.1998 Optimisation of the roller compaction process: impact of granulate and tablet quality
Sam Corveleyn 20.10.1998 Evaluation of maltodextrines as excipiens with the formulation of lyophilised pharmaceutical forms
Fang Zhou 10.02.1998 Matrix pellets based on microcrystalline waxes and starches
Jody Voorspoels 23.10.1997 Orale mucosale absorptie van geneesmiddelen via een bioadhesieve tablet
Chris Vervaet 23.06.1997 Influence of process- and formulation parameters on the quality of pellets, produced by use of extrusion/spheronisation
Maria Deolinda Ferreira Dos Santos 30.04.1997 Bioavailability of doxycyline in turkeys and its potential use for the treatment of chlomydia psittaci infections via drinking water medication