Basic and Translational Endocrinology

The Basic and Translational Endocrinology (BaTE) lab studies sex hormone signaling in non-reproductive target tissues including the musculoskeletal system, liver and kidney. By combining mouse models of deficient sex hormone action with omics approaches, we aim to understand how sex hormone receptors regulate physiological processes in these tissues, and how this regulation is altered in clinically relevant situations such as metabolic dysfunction-associated steatotic liver disease and gender-affirming hormone therapy.

Infrastructure and techniques

Mouse breeding and handling, PCR, qRT-PCR, western blotting, ELISA, immunohistochemistry, cistromic and transcriptomic analyses

Staff

Scientific coordinator : Prof. Dr. Vanessa Dubois

Doctoral researchers: Sandra Calvo Blanco, Oriana Nobus, Bart Wouters, Boya Zhang

Contact

Prof. Dr. Vanessa Dubois

Basic and Translational Endocrinology (BaTE)

Department of Basic & Applied Medical Sciences

Faculty of Medicine & Health Sciences, Ghent University

Campus UZ Gent The Core Gate 37

C. Heymanslaan 10, 9000 Ghent, Belgium

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