Oncological Orthopaedics

Within this line of research, the 'Orthopaedics and Traumatology Research Group' focuses on both surgical and non-surgical research into sarcomas. This line of research is multidisciplinary (oncological orthopedics, surgery, experimental cancer research, medical oncology, pathology).

Research projects

Exploration of the role of extracellular vesicles (EVs) in the development of (lung) metastases in sarcoma patients

These EVs play a role in cancer progression by exchanging messages between cancer cells and other cells, both locally and remotely via the bloodstream.

  • researcher: Suzanne Fisher


The further development of a reliable and representative personalized pre-clinical sarcoma model

Standard and experimental therapeutic products can be tested before being administered to the patient. To be able to do this, we develop a co-clinical study with known in vitro and in vivo models such as (orthotope) xenografts derived from patients (PD(o)X).

  • researcher: Suzanne Fisher
  • funding: Kom op tegen Kanker (flemish NGO)


Improve function after limb-saving surgery

This includes the resection of musculoskeletal tumours and the reconstruction of the bone defect. This reconstruction can be performed in a biological (bone) or non-biological (reconstruction prostheses) way. In the clinical setting, improving surgical techniques can improve the patient's function, as well as avoid complications and reoperations.


  • Close collaboration with the clinical tumour task force of University Hospital Ghent



  • Gwen Sys, clinic head