PhD and Master dissertations

PhD dissertations

Name

Date

Title

Nathalie Bracke Dec 2016

Functional quality of somatropin derivatives: NOTA-modifications and peptides

Lieselotte Veryser Oct 2016

Analytical, pharmacokinetic and regulatory characterisation of selected plant N-alkylamides

Lien Taevernier

Sept 2016

Skin, mucosal and blood-brain barrier kinetics of model cyclic depsipeptides: the mycotoxins beauvericin & enniatins

Sofie Stalmans

Sept 2015

To what extent do cell-penetrating peptides selectively cross the blood-brain barrier?

Matthias D'Hondt Jan 2015

Towards a peptide implant: analytics, dry heat behavior and functional characterization.

Evelien Wynendaele

Dec 2014

Exploration of quorum sensing peptides : the missing link between microbiome and cancer outcome ?

Antita Adriaens

 

Dec 2013

Morphine and the canine brain: The influence of morphine on cerebral perfusion and 5-HT2A receptors.

Promotor: prof. I. Polis; Co-promotor: prof. B. De Spiegeleer

Jente Boonen Dec 2012

Functional quality of spilanthol, a plant N-alkylamide for dermal applications

Sylvia Van Dorpe

Feb 2012

Analytical characterization of the  blood-brain barrier transport of peptides

Bram Baert

Jan 2011

Functional quality of tropical drugs: analytical exploration of the Franz Diffusion Cell test.

Adel Pezeshki

Dec 2010

Physiology and pathophysiology of the mammary gland in primiparous cows with special emphasis to dry period length and experimental E.coli mastitis.

Promotor: prof. C. Burvenich; Co-promotor: prof. B. De Spiegeleer

Valentijn Vergote

Feb 2010

Quality analytics of peptide drugs: the obestatin case.

 

Master dissertations

  • Dorien De Swaef

“Solid phase synthesis of possible new selective iNOS-inhibitors.” (2016)

  • Sarah Vanwijnsberghe

“Antimicrobial peptides: a study on the influence of D-amino acids on antimicrobial and haemolytic activity.” (2016)

  • Evelien De Sutter

“Ontwikkeling van een HILIC-PDA methode voor de detectie van counterfeit peptide biopharmaceuticals.” (2016)

  • Jana Vandenbossche

“Optimization of a capillary electrophoresis method for E.Coli L-asparaginase in the context of the charge impurities quantification.” (2016)

  • Severine De Craemer

“Exploration of saliva sample preparation techniques for in vivo quorum sensing peptide UHPLC-MS/MS detection.” (2016)

  • Julie Cantoro

“Chemical synthesis of COMXRO-E-2 pheromone containing modified tryptophan.” (2015)

  • Laura Verspeelt

“Development of a quality control method for L-asparaginase using capillary electrophoresis.” (2015)

  • Janne Catelin

“Synthesis and purification of derivates of a bioactive neuropeptide.” (2015)

  • Valerie Van Laere

“High-throughput screening of antimicrobial peptides against Candida krusei and Cryptococcus neoformans.” (2015)

  • Lotte Ghijs

“Ontwikkeling van een screeningsmethode voor de detectie van slimming agents en PDE5-inhibitoren in illegale voedingssupplementen met behulp van Phase Optimized Liquid Chromatography (POP-LC).” (2015)

  • Charlotte De Vriendt 

“Liquid Chromatography in quality control, quality assurance and bioanalytics of artemisinin derivatives.” (2015)

  • Lisa Delahaye 

“Method development and validation of a HS-GC-FID method for the control of residual solvents in salicylic acid.” (2015)

  • Valerie Stynen

“Evaluation, qualification and validation of a rapid microbiological method: Biotrak.” (2015)

  • Jana Verstraete

“Novel SUB-1 inhibitors as possible antimalaria therapy.” (2015)

  • Nathan Debunne

“The synthesis and purification of a number of quorum sensing peptides.” (2015)

  • Sven De Troyer:

"Enniatin-containing medicines for topical use: quality-by-design risk assessment of composition variability." (2015)

  • Jolien De Waele:

"Development of a bioanalytical uhplc-ms/ms method for NMG in mouse brain." (2015)

  • Christoph Portier:

"Initial development of a bioanalytival method for quorum sensing peptides." (2015)

  • Martha Donadoni:
    "Quality evaluation of pediatric antimalarial powders for suspension from resource-limited countries." (2015)
  • Annelien Sercu:
    "Development of a bio-analytical method for the quantification of N-alkylamides in biological samples using UPLC-MS/MS." (2015)
  • Jonas Poppe:
    "Developmental aspects for the quality analysis of selected medicines." (2014)
  • Ellen Rogge:
    "Quantitative analysis and practical research of market artemisinin based combination formulations." (2014)
  • Stéphanie anderson:
    "Development of a Surface Acoustic Wave method for the functional quality control of selected somatropins." (2014)
  • Eline Grauls:
    "API loss during capsule preparation." (2013)
  • Karl-Jan Spittaels:
    "Development of a Surface Acoustic Wave method for the functional quality control of selected somatropins." (2013)
  • Lieselot Minne:
    "Isolatie en chemische karakterisatie van N-alkylamides uit plantenextracten en hun transdermal gedrag." (2013)
  • Flore Vermeersch:
    "Transdermaal onderzoek van twee conanokristal formulaties en twee cyclische depsipeptiden: beauvericine en enniatines." (2013)
  • Andy Van Damme:
    "Risk assessment of impurities in topically used excipients: acetol." (2012)
  • Laurens Deneve:
    "Toepassingen van Surface Acoustic Wave (SAW) in de farmaceutische wetenschappen." (2012)
  • Pieter-Jan Van Bockstal:
    "Een functionele kwaliteitsmonografie voor asparaginase." (2012)
  • Matthias Van Laethem:
    "Lipopeptides: column comparison and dry heat stress of polymyxin B sulphate."(2012, ManaMa)
  • Maxime Boucart:
    "Clusteren van quorum-sensing signaalpeptiden." (2011)
  • Jochem Vancoillie:
    "Vergelijking van methoden voor de activiteitsbepaling van asparaginase."(2011)
  • Iris Vandenbroek:
    "Kwantitatieve karakterisatie van het bloed-hersenbarriere (BHB) transport van nieuwe opioid peptiden." (2011)
  • Elien Deketelaere:
    "Droge hitte stabiliteit van busereline acetaat d.m.v. een quality-by-design benadering." (2011)
  • Wim Demaré:
    "Droge stress stabiliteit van een model peptide mengsel." (2010)
  • Celine Thierens:
    "Analytical development of 1,2,4-trioxane derivatives." (2010, ManaMa)
  • Elisa Desmet:
    "Fused-core Shell HPLC voor spilanthol, toegepast in transdermaal onderzoek." (2010)
  • Daphne Wiskerke:
    "Karakterisatie van NOTA-gemodificeerd somatropine." (2010)
  • Ingeborg Wallez:
    "Dejodinatiestudie van gejodieerde obestatine-derivaten." (2010)
  • Annelies Van Lerberghe:
    "Chromatografische karakterisatie van peptide: vergelijkende studie van kolommen." (2010)
  • Grégoire Bouchez:
    "Development of a new high-throughput method: ion mobility spectrometry versus high performance liquid chromatography." (2010, ManaMa)
  • Nele Clottens:
    "Kwaliteitsanalytiek van zalm calcitonine in een nasaal poeder." (2009)
  • Eline Halet:
    "Transmembraan gedrag van spilanthol doorheen huid en bucale mucosa." (2009)
  • Nathalie Pintelon:
    "Analytische karakterisatie van het bloed-hersen-barriëre transport van 3 opioïde peptides EM-1, EM-2 en CTAP." (2009)
  • Sara Vanneste:
    "Transdermaal gedrag van ibuprofen invloed van miconazole nitraat." (2009)
  • Cindy Blomme:
    "Gaschromatografie van polyonverzadigde vetzuren." (2008)
  • Evelyn De Backer:
    "Karakterisatie van peptide geneesmiddelen: in vitro metabolisatie." (2008)
  • Anavarapu Sudhakar:
    "A comparative in-vitro permeation study of testosterone from different commercially available preparations." (2008)
  • Céline Thierens:
    "Ion mobility Spectrometry: een bruikbare analytische techniek bij in-vitro transdermale experimenten." (2008)
  • Sofie Van Houcke:
    "Kwaliteitscontrole in de karakterisatie van transdermale geneesmiddelen: ontwikkeling van SST voor in vitro FDC huid testen." (2008)
  • Jente Boonen:
    "Karakterisatie van transdermale penetratie promotoren." (2007)
  • Roosmarijn De Cock:
    "Analyse van dermatologische testosteron preparaten". (2007)
  • Nils Stuerebaut:
    "Stress- en radiosterilisatie stabiliteitsonderzoek van enkele geselecteerde peptiden." (2007)
  • Sofie Langendries:
    "Bio-analyse van veterinaire drugs: methode-ontwikkeling voor bepaling van roxarsone in veevoeder." (2006)
  • Lindsay Van Horebeke:
    "Onderzoek naar prevalentie en classificatie van breuklijntabletten." (2006)