PhD en Master Dissertations
PhD dissertations
Name |
Date |
Title |
Xialong Xu |
Jan 2020 |
Title: Quality characterization of raw materials used in advanced therapy medicinal products: HEPES, APMg and album |
Han Yao |
Oct 2019 |
Title: Quality exploration of L-asparaginase: analytical characterization |
Steven Janvier |
Jan.2019 |
Title: Hazard analysis of falsified peptide 'medicines' |
Bert Gevaert |
Jan 2017 |
Exploration of cryptic peptides: analytical, pharmacoloical and regulatory contributions |
Sultan Suleman |
Feb 2016 |
Quality of selected medicines in Ethiopia: analytical and regulatory contribution |
Nathalie Bracke |
Dec 2016 |
Functional quality of somatropin derivatives: NOTA-modifications and peptides |
Lieselotte Veryser |
Oct 2016 |
Analytical, pharmacokinetic and regulatory characterisation of selected plant N-alkylamides |
Lien Taevernier |
Sept 2016 |
Skin, mucosal and blood-brain barrier kinetics of model cyclic depsipeptides: the mycotoxins beauvericin & enniatins |
Sofie Stalmans |
Sept 2015 |
To what extent do cell-penetrating peptides selectively cross the blood-brain barrier? |
Matthias D'Hondt |
Jan 2015 |
Towards a peptide implant: analytics, dry heat behavior and functional characterization. |
Evelien Wynendaele |
Dec 2014 |
Exploration of quorum sensing peptides : the missing link between microbiome and cancer outcome ? |
Antita Adriaens |
Dec 2013 |
Morphine and the canine brain: The influence of morphine on cerebral perfusion and 5-HT2A receptors. Promotor: prof. I. Polis; Co-promotor: prof. B. De Spiegeleer |
Jente Boonen |
Dec 2012 |
Functional quality of spilanthol, a plant N-alkylamide for dermal applications |
Sylvia Van Dorpe |
Feb 2012 |
Analytical characterization of the blood-brain barrier transport of peptides |
Bram Baert |
Jan 2011 |
Functional quality of tropical drugs: analytical exploration of the Franz Diffusion Cell test. |
Adel Pezeshki |
Dec 2010 |
Physiology and pathophysiology of the mammary gland in primiparous cows with special emphasis to dry period length and experimental E.coli mastitis. Promotor: prof. C. Burvenich; Co-promotor: prof. B. De Spiegeleer |
Valentijn Vergote |
Feb 2010 |
Quality analytics of peptide drugs: the obestatin case. |
Master dissertations
-
Hannah Hirmz
“Alleviating peptide adsorption: an ecological and financially sustainable anti-adsorption diluent alternative.” (2020)
- Merel Wauters
“Effects of selected QSPs on host muscle.” (2020)
- Sebastiaan Dhaenens
“Presence of EntF metabolite in human faeces.” (2020)
- Phaedra Snauwaert
“Target elucidation of the EntF metabolite in HCT-8 cells.” (2020)
- Ella Vancraeynest
“Photolysis of CgCPA for selective therapy: principles and UPLC method development.” (2020)
-
Arnout Swaenen
“Development of a fusion peptide for miRNA-21 targeted treatment of Glioblastoma Multiforme.” (2020)
- Yani Ongena
“Het effect van quorum sensing peptiden op BV-2 microglia en SH-SY5Y neuroblasten.” (2019)
- Amélie Descamps
“Solid-phase synthesis and quality control of quorum sensing peptide derivatives.” (2019)
- Margot Poelman
“Kwaliteitscontrole voor NOTA-somatropine en Ga-NOTA-somatropine.” (2019)
- Dorian Depuydt
“Detectie en stabiliteit van quorum sensing peptiden in biologische matrices.” (2019)
- Van Langenhove Selien
“Quorum sensing moleculen en sarcopenie: in vitro proof-of-concept.” (2019)
- Djoa Jacintha
“Verklaren van de MTT effecten van geselecteerde quorum sensing peptiden op C2C12 cellen.” (2019)
- Shary Hermans
“HILIC and RP-chromatography for the detection of quorum sensing peptides.” (2018)
- Charlotte Masschelein
“Perceptions of pharmacists in West-Flanders towards probiotics.” (2018)
- Karen Herman
“Human Albumin and L-Ascorbic Acid 2-Phosphate Magnesium Salt as Raw Materials in the ATMP Production Process: Quality Assessments.” (2018)
- Miguel Colpaert
“In pursuit of quality medicines: Residual API on packaging as GMP-marker?” (2018)
- Shauni Patyn
“The influence of bacterial quorum sensing molecules on muscle cells.” (2018)
- Eva Dhondt
“The effects of quorum sensing peptides on mammalian cells.” (2018)
- Sara Develter
“Solid-phase peptide synthesis of the quorum sensing peptide SDLPFEH and some derivatives.” (2018)
- Hanne Jansen
“Relevance of in vitro and in vivo models to predict human effects in drug cardiovascular safety assessment.” (2018)
- Charlotte Goethals
“CE and MS contribution to E.coli asparaginase analytical characterization.” (2017)
- Vincent Van Brussel
“Viscosity of a hydrocortisone ointment: QbD method development and validation - Dermatokinetic study.” (2017)
- Jan Goelen
“Exploring turbidimetry and isothermal microcalorimetry as a tool for susceptibility testing and biofilm research.” (2017)
- Elisa De Pauw
“Optimalisatie van in vitro assays voor het bepalen van de pyrogeniciteit en het hemolytisch potentieel van illegal peptidepreparaten.” (2017)
- Christina Soto Fernandez
“Screening of surface acoustic wave ligand immobilization strategies for E.coli L-asparaginase” (2017)
- Dorien De Swaef
“Solid phase synthesis of possible new selective iNOS-inhibitors.” (2016)
- Sarah Vanwijnsberghe
“Antimicrobial peptides: a study on the influence of D-amino acids on antimicrobial and haemolytic activity.” (2016)
- Evelien De Sutter
“Ontwikkeling van een HILIC-PDA methode voor de detectie van counterfeit peptide biopharmaceuticals.” (2016)
- Jana Vandenbossche
“Optimization of a capillary electrophoresis method for E.Coli L-asparaginase in the context of the charge impurities quantification.” (2016)
- Severine De Craemer
“Exploration of saliva sample preparation techniques for in vivo quorum sensing peptide UHPLC-MS/MS detection.” (2016)
- Julie Cantoro
“Chemical synthesis of COMXRO-E-2 pheromone containing modified tryptophan.” (2015)
- Laura Verspeelt
“Development of a quality control method for L-asparaginase using capillary electrophoresis.” (2015)
- Janne Catelin
“Synthesis and purification of derivates of a bioactive neuropeptide.” (2015)
- Valerie Van Laere
“High-throughput screening of antimicrobial peptides against Candida krusei and Cryptococcus neoformans.” (2015)
- Lotte Ghijs
“Ontwikkeling van een screeningsmethode voor de detectie van slimming agents en PDE5-inhibitoren in illegale voedingssupplementen met behulp van Phase Optimized Liquid Chromatography (POP-LC).” (2015)
- Charlotte De Vriendt
“Liquid Chromatography in quality control, quality assurance and bioanalytics of artemisinin derivatives.” (2015)
- Lisa Delahaye
“Method development and validation of a HS-GC-FID method for the control of residual solvents in salicylic acid.” (2015)
- Valerie Stynen
“Evaluation, qualification and validation of a rapid microbiological method: Biotrak.” (2015)
- Jana Verstraete
“Novel SUB-1 inhibitors as possible antimalaria therapy.” (2015)
- Nathan Debunne
“The synthesis and purification of a number of quorum sensing peptides.” (2015)
- Sven De Troyer:
"Enniatin-containing medicines for topical use: quality-by-design risk assessment of composition variability." (2015)
- Jolien De Waele:
"Development of a bioanalytical uhplc-ms/ms method for NMG in mouse brain." (2015)
- Christoph Portier:
"Initial development of a bioanalytival method for quorum sensing peptides." (2015)
- Martha Donadoni:
"Quality evaluation of pediatric antimalarial powders for suspension from resource-limited countries." (2015) - Annelien Sercu:
"Development of a bio-analytical method for the quantification of N-alkylamides in biological samples using UPLC-MS/MS." (2015) - Jonas Poppe:
"Developmental aspects for the quality analysis of selected medicines." (2014) - Ellen Rogge:
"Quantitative analysis and practical research of market artemisinin based combination formulations." (2014) - Stéphanie anderson:
"Development of a Surface Acoustic Wave method for the functional quality control of selected somatropins." (2014) - Eline Grauls:
"API loss during capsule preparation." (2013) - Karl-Jan Spittaels:
"Development of a Surface Acoustic Wave method for the functional quality control of selected somatropins." (2013) - Lieselot Minne:
"Isolatie en chemische karakterisatie van N-alkylamides uit plantenextracten en hun transdermal gedrag." (2013) - Flore Vermeersch:
"Transdermaal onderzoek van twee conanokristal formulaties en twee cyclische depsipeptiden: beauvericine en enniatines." (2013) - Andy Van Damme:
"Risk assessment of impurities in topically used excipients: acetol." (2012) - Laurens Deneve:
"Toepassingen van Surface Acoustic Wave (SAW) in de farmaceutische wetenschappen." (2012) - Pieter-Jan Van Bockstal:
"Een functionele kwaliteitsmonografie voor asparaginase." (2012) - Matthias Van Laethem:
"Lipopeptides: column comparison and dry heat stress of polymyxin B sulphate."(2012, ManaMa) - Maxime Boucart:
"Clusteren van quorum-sensing signaalpeptiden." (2011) - Jochem Vancoillie:
"Vergelijking van methoden voor de activiteitsbepaling van asparaginase."(2011) - Iris Vandenbroek:
"Kwantitatieve karakterisatie van het bloed-hersenbarriere (BHB) transport van nieuwe opioid peptiden." (2011) - Elien Deketelaere:
"Droge hitte stabiliteit van busereline acetaat d.m.v. een quality-by-design benadering." (2011) - Wim Demaré:
"Droge stress stabiliteit van een model peptide mengsel." (2010) - Celine Thierens:
"Analytical development of 1,2,4-trioxane derivatives." (2010, ManaMa) - Elisa Desmet:
"Fused-core Shell HPLC voor spilanthol, toegepast in transdermaal onderzoek." (2010) - Daphne Wiskerke:
"Karakterisatie van NOTA-gemodificeerd somatropine." (2010) - Ingeborg Wallez:
"Dejodinatiestudie van gejodieerde obestatine-derivaten." (2010) - Annelies Van Lerberghe:
"Chromatografische karakterisatie van peptide: vergelijkende studie van kolommen." (2010) - Grégoire Bouchez:
"Development of a new high-throughput method: ion mobility spectrometry versus high performance liquid chromatography." (2010, ManaMa) - Nele Clottens:
"Kwaliteitsanalytiek van zalm calcitonine in een nasaal poeder." (2009) - Eline Halet:
"Transmembraan gedrag van spilanthol doorheen huid en bucale mucosa." (2009) - Nathalie Pintelon:
"Analytische karakterisatie van het bloed-hersen-barriëre transport van 3 opioïde peptides EM-1, EM-2 en CTAP." (2009) - Sara Vanneste:
"Transdermaal gedrag van ibuprofen invloed van miconazole nitraat." (2009) - Cindy Blomme:
"Gaschromatografie van polyonverzadigde vetzuren." (2008) - Evelyn De Backer:
"Karakterisatie van peptide geneesmiddelen: in vitro metabolisatie." (2008) - Anavarapu Sudhakar:
"A comparative in-vitro permeation study of testosterone from different commercially available preparations." (2008) - Céline Thierens:
"Ion mobility Spectrometry: een bruikbare analytische techniek bij in-vitro transdermale experimenten." (2008) - Sofie Van Houcke:
"Kwaliteitscontrole in de karakterisatie van transdermale geneesmiddelen: ontwikkeling van SST voor in vitro FDC huid testen." (2008) - Jente Boonen:
"Karakterisatie van transdermale penetratie promotoren." (2007) - Roosmarijn De Cock:
"Analyse van dermatologische testosteron preparaten". (2007) - Nils Stuerebaut:
"Stress- en radiosterilisatie stabiliteitsonderzoek van enkele geselecteerde peptiden." (2007) - Sofie Langendries:
"Bio-analyse van veterinaire drugs: methode-ontwikkeling voor bepaling van roxarsone in veevoeder." (2006) - Lindsay Van Horebeke:
- "Onderzoek naar prevalentie en classificatie van breuklijntabletten." (2006)