PhD dissertations

Master dissertations

• Hannah Hirmz

“Alleviating peptide adsorption: an ecological and financially sustainable anti-adsorption diluent alternative.” (2020)

• Merel Wauters

“Effects of selected QSPs on host muscle.” (2020)

• Sebastiaan Dhaenens

“Presence of EntF metabolite in human faeces.” (2020)

• Phaedra Snauwaert

“Target elucidation of the EntF metabolite in HCT-8 cells.” (2020)

• Ella Vancraeynest

“Photolysis of CgCPA for selective therapy: principles and UPLC method development.” (2020)

• Arnout Swaenen

“Development of a fusion peptide for miRNA-21 targeted treatment of Glioblastoma Multiforme.” (2020)

• Yani Ongena

“Het effect van quorum sensing peptiden op BV-2 microglia en SH-SY5Y neuroblasten.” (2019)

• Amélie Descamps

“Solid-phase synthesis and quality control of quorum sensing peptide derivatives.” (2019)

• Margot Poelman

“Kwaliteitscontrole voor NOTA-somatropine en Ga-NOTA-somatropine.” (2019)

• Dorian Depuydt

“Detectie en stabiliteit van quorum sensing peptiden in biologische matrices.” (2019)

• Van Langenhove Selien

“Quorum sensing moleculen en sarcopenie: in vitro proof-of-concept.” (2019)

• Djoa Jacintha

“Verklaren van de MTT effecten van geselecteerde quorum sensing peptiden op C2C12 cellen.” (2019)

• Shary Hermans

“HILIC and RP-chromatography for the detection of quorum sensing peptides.” (2018)

• Charlotte Masschelein

“Perceptions of pharmacists in West-Flanders towards probiotics.” (2018)

• Karen Herman

“Human Albumin and L-Ascorbic Acid 2-Phosphate Magnesium Salt as Raw Materials in the ATMP Production Process: Quality Assessments.” (2018)

• Miguel Colpaert

“In pursuit of quality medicines: Residual API on packaging as GMP-marker?” (2018)

• Shauni Patyn

“The influence of bacterial quorum sensing molecules on muscle cells.” (2018)

• Eva Dhondt

“The effects of quorum sensing peptides on mammalian cells.” (2018)

•  Sara Develter

“Solid-phase peptide synthesis of the quorum sensing peptide SDLPFEH and some derivatives.” (2018)

• Hanne Jansen

“Relevance of in vitro and in vivo models to predict human effects in drug cardiovascular safety assessment.” (2018)

• Charlotte Goethals

“CE and MS contribution to E.coli asparaginase analytical characterization.” (2017)

• Vincent Van Brussel

“Viscosity of a hydrocortisone ointment: QbD method development and validation - Dermatokinetic study.” (2017)

• Jan Goelen

“Exploring turbidimetry and isothermal microcalorimetry as a tool for susceptibility testing and biofilm research.” (2017)

• Elisa De Pauw

“Optimalisatie van in vitro assays voor het bepalen van de pyrogeniciteit en het hemolytisch potentieel van illegal peptidepreparaten.” (2017)

• Christina Soto Fernandez

“Screening of surface acoustic wave ligand immobilization strategies for E.coli L-asparaginase” (2017)

• Dorien De Swaef

“Solid phase synthesis of possible new selective iNOS-inhibitors.” (2016)

• Sarah Vanwijnsberghe

“Antimicrobial peptides: a study on the influence of D-amino acids on antimicrobial and haemolytic activity.” (2016)

• Evelien De Sutter

“Ontwikkeling van een HILIC-PDA methode voor de detectie van counterfeit peptide biopharmaceuticals.” (2016)

• Jana Vandenbossche

“Optimization of a capillary electrophoresis method for E.Coli L-asparaginase in the context of the charge impurities quantification.” (2016)

• Severine De Craemer

“Exploration of saliva sample preparation techniques for in vivo quorum sensing peptide UHPLC-MS/MS detection.” (2016)

• Julie Cantoro

“Chemical synthesis of COMX_RO-E-2 pheromone containing modified tryptophan.” (2015)

• Laura Verspeelt

“Development of a quality control method for L-asparaginase using capillary electrophoresis.” (2015)

• Janne Catelin

“Synthesis and purification of derivates of a bioactive neuropeptide.” (2015)

• Valerie Van Laere

“High-throughput screening of antimicrobial peptides against Candida krusei and Cryptococcus neoformans.” (2015)

• Lotte Ghijs

“Ontwikkeling van een screeningsmethode voor de detectie van slimming agents en PDE5-inhibitoren in illegale voedingssupplementen met behulp van Phase Optimized Liquid Chromatography (POP-LC).” (2015)

• Charlotte De Vriendt 

“Liquid Chromatography in quality control, quality assurance and bioanalytics of artemisinin derivatives.” (2015)

• Lisa Delahaye 

“Method development and validation of a HS-GC-FID method for the control of residual solvents in salicylic acid.” (2015)

• Valerie Stynen

“Evaluation, qualification and validation of a rapid microbiological method: Biotrak.” (2015)

• Jana Verstraete

“Novel SUB-1 inhibitors as possible antimalaria therapy.” (2015)

• Nathan Debunne

“The synthesis and purification of a number of quorum sensing peptides.” (2015)

• Sven De Troyer:

"Enniatin-containing medicines for topical use: quality-by-design risk assessment of composition variability." (2015)

• Jolien De Waele:

"Development of a bioanalytical uhplc-ms/ms method for NMG in mouse brain." (2015)

• Christoph Portier:

"Initial development of a bioanalytival method for quorum sensing peptides." (2015)

• Martha Donadoni:
  "Quality evaluation of pediatric antimalarial powders for suspension from resource-limited countries." (2015)
• Annelien Sercu:
  "Development of a bio-analytical method for the quantification of N-alkylamides in biological samples using UPLC-MS/MS." (2015)
• Jonas Poppe:
  "Developmental aspects for the quality analysis of selected medicines." (2014)
• Ellen Rogge:
  "Quantitative analysis and practical research of market artemisinin based combination formulations." (2014)
• Stéphanie anderson:
  "Development of a Surface Acoustic Wave method for the functional quality control of selected somatropins." (2014)
• Eline Grauls:
  "API loss during capsule preparation." (2013)
• Karl-Jan Spittaels:
  "Development of a Surface Acoustic Wave method for the functional quality control of selected somatropins." (2013)
• Lieselot Minne:
  "Isolatie en chemische karakterisatie van N-alkylamides uit plantenextracten en hun transdermal gedrag." (2013)
• Flore Vermeersch:
  "Transdermaal onderzoek van twee conanokristal formulaties en twee cyclische depsipeptiden: beauvericine en enniatines." (2013)
• Andy Van Damme:
  "Risk assessment of impurities in topically used excipients: acetol." (2012)
• Laurens Deneve:
  "Toepassingen van Surface Acoustic Wave (SAW) in de farmaceutische wetenschappen." (2012)
• Pieter-Jan Van Bockstal:
  "Een functionele kwaliteitsmonografie voor asparaginase." (2012)
• Matthias Van Laethem:
  "Lipopeptides: column comparison and dry heat stress of polymyxin B sulphate."(2012, ManaMa)
• Maxime Boucart:
  "Clusteren van quorum-sensing signaalpeptiden." (2011)
• Jochem Vancoillie:
  "Vergelijking van methoden voor de activiteitsbepaling van asparaginase."(2011)
• Iris Vandenbroek:
  "Kwantitatieve karakterisatie van het bloed-hersenbarriere (BHB) transport van nieuwe opioid peptiden." (2011)
• Elien Deketelaere:
  "Droge hitte stabiliteit van busereline acetaat d.m.v. een quality-by-design benadering." (2011)
• Wim Demaré:
  "Droge stress stabiliteit van een model peptide mengsel." (2010)
• Celine Thierens:
  "Analytical development of 1,2,4-trioxane derivatives." (2010, ManaMa)
• Elisa Desmet:
  "Fused-core Shell HPLC voor spilanthol, toegepast in transdermaal onderzoek." (2010)
• Daphne Wiskerke:
  "Karakterisatie van NOTA-gemodificeerd somatropine." (2010)
• Ingeborg Wallez:
  "Dejodinatiestudie van gejodieerde obestatine-derivaten." (2010)
• Annelies Van Lerberghe:
  "Chromatografische karakterisatie van peptide: vergelijkende studie van kolommen." (2010)
• Grégoire Bouchez:
  "Development of a new high-throughput method: ion mobility spectrometry versus high performance liquid chromatography." (2010, ManaMa)
• Nele Clottens:
  "Kwaliteitsanalytiek van zalm calcitonine in een nasaal poeder." (2009)
• Eline Halet:
  "Transmembraan gedrag van spilanthol doorheen huid en bucale mucosa." (2009)
• Nathalie Pintelon:
  "Analytische karakterisatie van het bloed-hersen-barriëre transport van 3 opioïde peptides EM-1, EM-2 en CTAP." (2009)
• Sara Vanneste:
  "Transdermaal gedrag van ibuprofen invloed van miconazole nitraat." (2009)
• Cindy Blomme:
  "Gaschromatografie van polyonverzadigde vetzuren." (2008)
• Evelyn De Backer:
  "Karakterisatie van peptide geneesmiddelen: in vitro metabolisatie." (2008)
• Anavarapu Sudhakar:
  "A comparative in-vitro permeation study of testosterone from different commercially available preparations." (2008)
• Céline Thierens:
  "Ion mobility Spectrometry: een bruikbare analytische techniek bij in-vitro transdermale experimenten." (2008)
• Sofie Van Houcke:
  "Kwaliteitscontrole in de karakterisatie van transdermale geneesmiddelen: ontwikkeling van SST voor in vitro FDC huid testen." (2008)
• Jente Boonen:
  "Karakterisatie van transdermale penetratie promotoren." (2007)
• Roosmarijn De Cock:
  "Analyse van dermatologische testosteron preparaten". (2007)
• Nils Stuerebaut:
  "Stress- en radiosterilisatie stabiliteitsonderzoek van enkele geselecteerde peptiden." (2007)
• Sofie Langendries:
  "Bio-analyse van veterinaire drugs: methode-ontwikkeling voor bepaling van roxarsone in veevoeder." (2006)
• Lindsay Van Horebeke:
  

  "Onderzoek naar prevalentie en classificatie van breuklijntabletten." (2006)