HPLC: Waters Alliance 2695 Separations module with 2996 photodiode array detector, 2475 fluorescence detector and Empower software
HPLC: Waters Alliance 2695 Separations module with 2998 photodiode array detector, 2414 refractive index detector, Fraction Collector III and Empower software
HPLC: Waters Alliance 2695 Separations module with 2487 dual wavelength absorbance detector and Empower software
HPLC: Shimadzu CT0-10A column oven with Waters Alliance 2487 dual wavelength detector and Shimadzu C-R5A integrator
HPLC: Waters Breeze with 2487 dual wavelength absorbance detector and Breeze software
HPLC: Merck-Hitachi L-2130 pump, L-2400 single wavelength detector, column oven, Berthold gamma detector and EZChrom Elite software
LC-MS: Thermo Finnigan LCQ ion trap mass spectrometer with Spectrosystem LC (SN4000, SCM1000, P1000XR and AS3000), and Waters 2487 dual wavelength detector, Thermo Xcalibur and BioWorks software
UPLC: Waters Acquity UPLC H-class Bio QSM, sample manager, column heater and PDA detector.
UPLC-TQ-MS: XevoTM TQ-S (Waters) is designed for the most demanding quantitative UPLC®/MS/MS applications. It features are revolutionary new off-axis ion source technology (StepWaveTM) which increases even further the high sensitivity provided by Xevo TQ. This advance in performance allows accurate, robust, and reproducible measurements of compounds at very lower concentrations. Xevo TQ-S also features collision cell technology (ScanWaveTM) to provide enhanced spectral LC/MS/MS data acquisition capabilities to provide not only quantitative data, but also spectral MS/MS information.
GC: PerkinElmer Clarus 600, gas chromatograph with liquid autosampler and Turbomatrix 16 headspace autosampler, programmable split/splitless capillary injector and TotalChrom software.
Spectroscopy and related techniques
Spectrophotometer: Pharmacia Biotech Ultrosspec 4000 UV/Vis and Swift II software
Circular Dichroism: Jasco Circular dichroism (J-815 150-S) spectrometer with Spectra Manager 2, 150 W Xe, standard sample compartment, FMO-427S/15 emission monochromator with EX/Em spectrum measurement program, FDT-455 emission detector, MPTC-490S/15 multi-position CD/FL Peltier holder with temperatur control program and including SG-100855 collection lens holder and MLB-100 mini water circulation bath.
LCM: The Arcturus PixCell II laser capture microscope is a device widely applied in diverse research fields like proteomic, transcriptomic and genomic profiling, as well as bacterial identification. Our IR-LCM allows the soft isolation of a variety of tissues and cells under direct microscopic visualization using a thermoplastic polymer and is compatible with different staining and preservation methods.
Functional Biomedical-Biopharmaceutical equipment
Biosensor: Saw Instruments Sam5
Individual metabolic mouse-cages
Franz diffusion cell: Logan Instruments Corporation (3 x 6 cold; 1 x 6 radio-active)
Cryostat: Leica CM 1510 S (2)
Dissolution bath: Varian VV 7010, VK 750 D
Biological safety cabinet: Clean Air Techniek Class II EuroFlow EF/S-5