Focus on the introduction of proteomic technologies to address challenging questions in life sciences
Try to understand why proteins are N-terminally acetylated, study the function of N-terminal proteoforms, and develop technologies to identify cytolysis proteins as disease proxies
Our diversified proteomic toolbox makes us preferred catalysts for joint research projects
Interests
Proteomics
Protein modifications
Biomarkers
Single-cell proteomics
Current projects
Innovative Proteomics Approach to Identify Fluid Biomarkers for Frontotemporal Degeneration (FY20 Peer Reviewed Medical Research Program)
Probing the proteome structure in living cells (UGent, BOF)
A low-volume liquid dispenser for low-input to single-cell mass spectrometry-based proteomics (UGent, BOF)
Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process (FWO, iBOF)
Statistics for single-cell mass spectrometry-based proteomics (FWO)
Exploring stress granules to fortify plants against combinatorial stress (FWO)
Compartmentalized Complexity: Advancing Omics at the Organelle Level (FWO, large-scale research infrastructure call 2025)
Validation of a biomarker panel for the diagnosis of malignant pleural mesothelioma (Stand up against Cancer)
Automated sample preparation for single-cell mass spectrometry-based proteomics (Foundation against Cancer, Advanced technology equipment)
Elucidating Disease Heterogeneity and a Novel Therapeutic Approach for PRPH2-related Inherited Retinal Disease (Foundation Fighting Blindness - PRPH2 and Associated Retinal Diseases (PARD) Science Award)
