Translational Nuclear Receptor Lab

Research interests

  • Focus on nuclear receptor biology with an emphasis on protein-protein interactions, signal transduction and drug discovery
  • Understanding of nuclear receptor action mechanisms by combining omics technologies with standard molecular biology approaches
  • Development of screening platforms to reliably capture ligand profiles that steer nuclear receptors towards enhanced therapeutic benefit
  • Re-wiring of nuclear receptor cross-talk mechanisms towards unconventional, more favorable nuclear receptor heterodimerization
  • Bridge from fundamental knowledge to novel strategies for the benefit of sufferers from chronic inflammation, cancer and metabolic disorders 

More information about the Translational Nuclear Receptor Lab

More information about Prof. Karolien De Bosscher