Core Extracellulaire Vesicles
The CORE EV empowers the research community with deep expertise, advanced tools, and innovative technologies for studying extracellular vesicles and particles.
The CORE EV provides comprehensive support, from preparation and isolation to detailed characterization and analysis, helping researchers generate faster, more accurate, and more reliable insights in this rapidly evolving field.
Infrastructure
- Ultracentrifuge (2x) (Beckman Coulter, Optima XPN-80) with different rotor types (SW32.1, SW55)
- High-speed centrifuge (Beckman Coulter, Avanti JXN-26)
- Bench top centrifuge (3x) (Eppendorf, 5810 R)
- Laminar airflow (2x)
- Nanoparticle tracking analysis (Nanosight, LM10)
- Super-resolution microscope (Oxford NanoImager, ONI)
- Asymmetrical flow field-flow fractionation (AF4) (Eclipse, Wyatt) instrument coupled to a UV detector (Shimadzu, SPD-M20A), Multi-angle light scatter (MALS) detector (Wyatt, Dawn Helios-II) and Fluorescent light detector (Agilent, Infinity 1260)
Terms of use
1. Schedule an intake meeting
Contact us by email with a brief description of your EV-related project and propose a few possible time slots for an (online) intake meeting.
2. Complete the required training
Follow a basic training course in which the relevant techniques are taught. During your first set of (demo) samples, we provide close guidance to ensure a confident start.
3. Reserve instruments via the CFMS platform
All instruments must be booked through the CFMS platform.
4. Provide a budget for usage fees
Use of the Core Facility is subject to usage fees. Ensure that your project includes a cost center to cover these expenses.
5. Follow the equipment procedures and Core Facility guidelines
To use the equipment correctly and safely, follow the established procedures taught during training. Please also adhere to the general guidelines of the Core Facilities.
6. Acknowledge the Core Facility in your scientific output
To support the continuation and funding of the Core Facility, it is mandatory to acknowledge the facility in your publications and other scientific output. You can find the guidelines for proper acknowledgment here.