The UGent NGS Core is equipped (in-house) with state-of-the-art sample preparation systems that enable highly efficient, accurate, and automated processing for a wide variety of sample types. Additionally, the facility provides access to a diverse array of cutting-edge sequencing platforms, ensuring the scalability and precision required to meet the specific needs and scope of your project.
MiSeq
The MiSeq benchtop sequencer is designed for smaller-scale projects, making it ideal for targeted applications such as gene / amplicon sequencing, metagenomics, and microbial genome assembly. With a read output ranging from 1 million to 25 million reads, the MiSeq excels in narrowly focused applications.
MiSeq FGx Sequencing System
The MiSeq FGx Sequencing System is the first fully validated next-generation sequencing (NGS) instrument specifically designed for forensic genomics. It can process up to 96 combined SNP and STR libraries in a single run, conserving valuable samples while delivering robust performance. This system enables the development of comprehensive DNA profiles from various sample types, including high-quality genomic DNA (gDNA), as well as degraded, mixed, and limited samples.
Novaseq X
The NovaSeq X System delivers scalable ultra-high-throughput sequencing with unmatched flexibility, supporting a wide range of sequencing methods, genomes, and project scales.
PromethION
The Oxford Nanopore Technologies PromethION is a large-scale, single-molecule, real-time sequencing platform that delivers long reads with high consensus accuracy. Its capabilities make it ideal for whole-genome sequencing, de novo assemblies, and metagenomic analysis of viral populations. Additionally, nanopore sequencing uniquely enables the direct detection of epigenetic modifications in both DNA and RNA, making it invaluable for advanced epigenetics research.
AVITI24 Sequencer
The AVITI24 Sequencer is a state-of-the-art integrated biology platform for sequencing and in situ multiomic analysis. Whether your research aims to identify pathways implicated in disease, uncover a compound’s mechanism of action, or understand cellular differentiation, AVITI24 with Teton™ CytoProfiling provides multiomic insights to address your most important scientific questions. With multiple read-outs from a single platform – including cellular morphology, RNA, and protein expression – the possibilities are limitless.
Multiomic Read-outs from a Single Sample: AVITI24 delivers comprehensive data on cellular morphology, RNA, and protein expression, all from one sample.
Flexible Experimental Design with Teton Flow Cells: Teton flow cells offer adaptability for various experimental setups and are compatible with a wide range of sample inputs.
Integrative Cytoprofiling Analyses: Cytoprofiling read-outs can be seamlessly integrated into diverse analyses to enhance understanding of differential expression, signaling pathways, and cell-cell interactions.
PacBio Revio
The PacBio Revio system is a high-throughput, long-read sequencing platform that excels in delivering highly accurate HiFi reads, making it well-suited for complex genomics applications. With its ability to produce long, highly accurate sequences, it is ideal for whole-genome sequencing, de novo assemblies, structural variant analysis, and transcriptomics. Moreover, the Revio system enables comprehensive epigenetic profiling by directly detecting base modifications, offering valuable insights for advanced genomic and epigenomic studies.
