Micro reactor systems

Description                                             

Different microreactor systems are available at our research group:

Labtrix® Start (Chemtrix)
Internal volume: 1, 5 or 10 µl depending on the reactor chip used
Temperature range: -15°C to 195°C
Pressures up to 25 bar
Wetted materials: glass, PEEK, PTFE, Techtron

KiloFlow® (Chemtrix)
Internal volume: 13 ml
Temperature range: 10°C to 150°C
Pressures up to 20 bar
Wetted materials: glass, PEEK, ETFE, perfluoroelastomer

X-CubeTM (ThalesNano)
Temperature range: 20°C to 200°C
Pressures up to 150 bar
Wetted material: stainless steel
Compatible with gases (H2, O2, ...)
Compatible with catalyst cartridges (Pd/C, Raney Ni, ...)

Uniqsis FlowSyn
Flow rates from 5 µl/min up to 10 ml/min
Glass static mixer + Teflon 5 ml coil reactor
10 bar BPR

In house assembled microreactor
PEEK T- or Y-mixer or ETFE T-mixer
PFA-tubing (0.5 mm internal diameter)

CPC® College System
2 ml microreactor (stainless steel) + 45 ml residence time unit

Bruker Avance-III 400 MHz NMR Spectrometer equipped with BRUKER 5 mm BBFO 400 MHz Z-gradient high resolution probe

Description

State-of-the-art NMR spectrometer equipped with an observe broadband high resolution probe, fitted with an actively shielded single axis Z-gradient for 5 mm sample diameters and 400 MHz standard-bore or wide-bore magnets. The inner NMR coil can be tuned to observe ¹⁹F or any nucleus in the range from ³¹P to ¹⁵N. The outer NMR coil is tuned for either ¹H decoupling or observation. The probe is fitted with a ²H lock channel and automatic tuning and matching (ATM).

Signal/Noise

¹⁹F sensitivity  ≥250:1  (TFT sample, with 1H decoupling)

³¹P sensitivity  ≥140:1  (TPP sample)

¹³C sensitivity  ≥160:1  (ASTM sample)

¹⁵N sensitivity  ≥20:1  (90% formamide sample)

¹H sensitivity  ≥250:1  (0.1% EB sample, 2ppm noise)

Pulse Widths

¹⁹F pulse width  ≤15μs  (TFT sample)

³¹P pulse width  ≤15μs  (TPP sample)

¹³C pulse width  ≤10μs  (ASTM sample)

¹⁵N pulse width  ≤18μs  (90% formamide sample)

¹H pulse width  ≤15μs  (0.1% EB sample)

Lineshape

¹³C spinning lineshape  ≤0.2/2/4 Hz  (50%/0.55%/0.11%, ASTM)

¹H spinning lineshape  ≤0.6/6/12 Hz  (50%/0.55%/0.11%, 1% CHCl3)

Z-gradient

The probe is fitted with an actively shielded single axis Z-gradient.

Maximum gradient strength is 50 gauss/cm

Variable Temperature Range

Variable temperature range is from -150°C to +150°C*

Liquid chromatography - Mass spectrometry

Agilent 1100 LC/MSD SL - Agilent 1200 LC - 1100 Series MSD VL

HPLC : UV detection by DAD

MS : ESI -quadrole (single-quad) - electron multiplier

Agilent 1100 Prep LC

HPLC : VWD detection - fraction collector

Perkin Elmer FT-IR system

Description

PerkinElmer FT-IR system, spectrum BX with ATR (attenuated Total Reflectance) accessory (ZnSe crystal)

• solid and liquid sampling
• no sample preparation
• improved sample to sample reproducibility
• minimized user to user spectral variation

GC-MS Agilent 6890 Plus

Description

The Agilent 6890 Plus GC system is coupled to a quadropole mass selective spectrometer 5793 MSD

Gerstel CIS-4 PTV injector

Gerstel MPS2 autosampler has various introduction techniques: liquid, dynamic headspace, SPME and thermal absorption.

Organic Elemental Analysis
2400 Series II CHNS/O Elemental Analyser

One analyser with three modes of operation : CHN, CHNS and Oxygen

Advanced cumbustion design for handling virtually any type of samples

Frontal chromatography for simple , reliable and accurate measurements

Automated weight entry

Analytical detector range (element range (mgs)):

• C: 0.001 - 3.6
• H: 0.001 - 1.0
• N: 0.001 - 6.0
• S: 0.001 - 2.0
• O: 0.001 - 2.0