Services

Solid phase synthesis of peptides and small heterocyclic pepeptidomimetics

• synthetic approaches via automated solid phase synthesis
• peptides synthesis, modification and conjugation
• methodologies for selective chemical modification of specific residues within peptides
• construction of conformationally restricted peptides

Solid phase synthesis of oligonucleotides and analogues

• oligonucleotide synthesis, modification and conjugation including DNA, RNA, 2'-OMe RNA and PNA
• construction or reactive probes incorporating caged reactive functionalities for nucleic acid target identification
• antisense and antigene strategies

Purification of peptides and small molecules

• reversed phase purification of peptides and small molecules
• large scale purification, up to 300 mg sample per injection
• automated fraction sampling
• freeze drying of the purified fraction