PhD Student

Last application date
Nov 30, 2022 00:00
Department
GE31 - Department of Biomolecular Medicine
Contract
Limited duration
Degree
Master in Science (Bioengineering, Biochemistry-Biotechnology, Biomedical Sciences, Medicine, or related)
Occupancy rate
100%
Vacancy type
Research staff

Job description

INTRODUCTION

The lab of Translational Onco-genomics and Bioinformatics (supervised by prof. dr. ir. Katleen De Preter) at the Department of Biomolecular Medicine (UGent, VIB) and the Pathology lab (supervised by prof. dr. Jo Van Dorpe and prof. dr. David Creytens) at the Department of Diagnostic Sciences (UGent) have an open position for a highly motivated biomedical researcher with expertise and interest in translational cancer research. More information on the teams and the research focus can be found at www.crig.ugent.be/en/prof-katleen-de-preter-phd, www.crig.ugent.be/en/prof-jo-van-dorpe-md-phd and www.crig.ugent.be/en/prof-david-creytens-md-phd.

ABOUT GHENT UNIVERSITY

Ghent University is a world of its own. Employing more than 8,000 people, it is actively involved in education and research, management and administration, as well as technical and social service provision on a daily basis. It is one of the largest, most exciting employers in the area and offers great career opportunities. With its 11 faculties and more than 80 departments offering state-of-the-art study programs grounded in research in a wide range of academic fields, Ghent University is a logical choice for its staff and students.

THE PhD PROJECT

Omics based strategies ((epi-)genomics, transcriptomics, proteomics, …) are opening unprecedented potential for developing novel precision oncology tools for improved diagnosis, prognosis and therapy response prediction of cancer patients. Liquid biopsies are now offering a great potential for non-invasive exploration of circulating tumor nucleic acids and cells.
Recently, our team has implemented DNA methylation sequencing on tumor tissue and liquid biopsy samples of cancer patients to allow improved diagnosis and classification of the tumor. The new PhD student will further develop, optimize, implement, apply and validate this novel approach (both at the analytical and bio-informatic side). The final aim of the project is to improve diagnosis of adult cancer patients with an unknown primary tumor location.
The research in our team is supported by several grants focused on DNA and RNA sequencing generated on bulk as well as single cancer cells and nucleic acids obtained using invasive and non-invasive sampling.

Job profile

WHAT WE ARE LOOKING FOR

  • You have a Master in Science (Bioengineering, Biochemistry-Biotechnology, Biomedical Sciences, Medicine, or related).
  • You have knowledge and insights in cancer biology and genomics.
  • Expertise with laboratory work in a molecular/genetic lab, including DNA- and/or RNA-sequencing technologies, is a plus.
  • Some expertise in bio-informatics and data-mining is a plus.
  • You have analytical problem-solving skills, you are a team player, creative, critical, and open-minded.
  • You have excellent oral and written communication skills in English.

WHAT WE CAN OFFER YOU

You will work in a multidisciplinary environment under the supervision of senior scientists in the TOBI lab and the Pathology lab and within the broader framework of the Cancer Research Institute Ghent (crig.ugent.be). We offer:

  • A PhD position for at least one year (including a 6-month evaluation period) after which you will apply for a personal PhD grant with FWO, BOF, …
  • Participation in an exciting and rapidly evolving research area of clinically translational genomics,
  • Being part of a research team operating at international level and dedicated to improving survival of patients with cancer,
  • State-of-the-art technology and facilities ((epi-)genomics, transcriptomics, (single-cell) sequencing, bioinformatics, etc),
  • The opportunity to work in a dynamic and interdisciplinary academic research environment,
  • Embedding within top-research teams with a broad range of expertise,
  • Collaboration with and assistance of wet-lab scientists in the design, analysis and interpretation of cancer genomics data.

How to apply

Send your application to katleen.depreter@ugent.be before the applicatoin deadline (30/11/2022). We do not accept late applications.

Your application must include the following documents:

  • Your CV and an overview of your study results (merged into one pdf file)
  • 'Cover letter': your application letter in pdf format
  • ‘Diploma’: a transcript of the required degree (if already in your possession). If you have a foreign diploma in a language other than our national languages (Dutch, French or German) or English, please add a translation in one of the mentioned languages.
  • optional: a reference letter, an overview of your study results, …


As Ghent University maintains an equal opportunities and diversity policy, everyone is encouraged to apply for this position.