Postdoctoral fellow

Last application date
Dec 04, 2022 00:00
Department
DI07 - Department of Veterinary and Biosciences
Contract
Limited duration
Degree
PhD in Bioscience Engineering, Biomedical Sciences, Biotechnology, Molecular Biology, Pharmaceutical Sciences, or other equivalent discipline.
Occupancy rate
100%
Vacancy type
Research staff

Job description

The Laboratory of Gene Therapy at Ghent University has a vacancy for an excellent and motivated junior postdoctoral researcher with expertise related to nanomedicine, mRNA vaccines, mRNA therapeutics, nanoparticle based pharmaceutical formulations or molecular engineering. You will work on the formulation and preclinical evaluation of mRNA vaccines against infectious diseases. The intended starting date of the position is February or March 2023.

What can we offer you?

  • A bursary contract for a duration of one year that can be extended if a positive evaluation and sufficient grants are available.
  • A full-time position.
  • A multidisciplinary team and cooperative team.
  • An international competitive salary including benefits.

About the Laboratory
The team of Prof. Niek Sanders works since 2007 on the development of synthetic mRNAs for protein replacement therapy and vaccination. At that time a handful researchers really believed that mRNA therapeutics could revolutionize modern medicine. The team uses modified and self-amplifying (sa) mRNA platforms and investigates the in vivo efficacy and innate immunogenicity of these mRNA platforms in preclinical models. Sanders’s team worked for example recently on switchable sa-mRNAs encoding erythropoietin and on sa-mRNA vaccines against Zika virus and SARS-CoV-2. In 2019 the team also started to investigate delivery systems for mRNA vaccines and mRNA therapeutics.

Job profile

You must have a FELASA C attest or equivalent EU accreditation for animal experimentation. Enclose a copy of the certificate with the application.

You are a junior international postdoctoral researcher in the field of nanomedicine with preferably experience with genetic (mRNA or DNA) vaccines or non-viral nanoparticle-based gene delivery systems.

You have hands-on experience with at least four of the following items: cell cultures, in vivo experiments in mice, molecular biology techniques, transfection experiments and the readouts of them, nanoparticle formulations, production of mRNA by in vitro transcription, bioinformatics tools, immunological assays.

You can demonstrate your excellence and hands-on skills by first author publications in peer reviewed journals.

You are able to start in February or March 2023.

You have excellent English communication skills (both oral and written).

You are highly motivated and can plan and conduct research accurately.

You can function well independently as well as in a team.

You can take initiative and have a hands-on mentality, perseverance and critical mind-set.

How to apply

Please send your application to Prof. Niek Sanders (Niek.Sanders@UGent.be) by December 4th, 2022.

Please include a single pdf in your application that combines the following elements:

  • FELASA attest or equivalent accreditation for animal experimentation obtained in the EU.
  • Motivation letter expressing your interest in and suitability for the project.
  • Detailed CV including publications and summary of past research activities.
  • A transcript of your Masters’ degrees and PhD diploma. If the language of your degrees or diplomas are not in English, French, Dutch or German please add a translation in English.
  • Optional, contact information of referees.

A shortlist of applicants will be made and these will be invited for interviews. The first review of applications will start immediately. When you are selected for and interview you will receive an e-mail before December 18th. Hence, if you do not receive an e-mail before that date this implies that you were not selected for the second round.