Lecture 'Meet the PhD Jury: Single cell omics benchmarking of data analysis tools and model-based dimension reduction'
- For whom
- Employees , Students
- When
- 27-05-2024 from 02:30 to 05:00
- Where
- Auditorium 8, Campus Ledeganck, Ledeganckstraat 35, 9000 Gent
- Language
- English
- Organizer
- Department of Applied Mathematics, Computer Science and Statistics - Faculty of Scienes
- Contact
- lieven.clement@ugent.be
14:30 - Charlotte Soneson, Single-cell method benchmarking - current state and future perspectives Many computational tools exist for a given task in single cell data analysis.
I will discuss the current state of the field of method benchmarking, which aims to rigorously compare the performance of different methods using well-studied datasets. I will also point to current challenges, and some efforts that we have taken over the years to make benchmarking more extensible and continuous.
15:15 - Davide Risso, Stochastic generalized matrix factorization for scalable analysis of single-cell RNA-seq
I will present a novel algorithm for estimating high-dimensional generalized matrix factorization models under generic exponential family likelihoods. On single-cell RNA-seq data, our method outperforms existing methods, demonstrating faster execution times while maintaining, or even enhancing, matrix reconstruction fidelity and accuracy.
16:00 - 17:00 Coffee break and Discussions