Equine Metabolic Plasticity

Vidal Moreno de Vega, Carmen
Faculteit Diergeneeskunde
Vakgroep Translationele Fysiologie, Infectiologie en Volksgezondheid
María del Carmen Vidal Moreno de Vega was born in Salamanca, Spain on the 5th of February 1990. She attended school in Maristas Champagnat in her hometown and then obtained her Bachelor’s degree in Biology in the University of Salamanca in 2015, and subsequently moved to Belgium to pursue a Master degree in Biomedical Sciences with a focus on infectious and tropical diseases in the University of Antwerp, which she achieved in 2017. After this, she worked briefly in the Malariology Unit at the Institute of Tropical Medicine in Antwerp. After this, she joined the team of the Comparative Physiology Research Group, Prof. Delesalle in 2018 as an assistant, which entails both education and research responsibilities. Her doctoral dissertation is about equine metabolic plasticity, where she investigated musculo-morpho-physiological parameters and the baseline metabolic profile of different horse breeds along with changes in glucose transporters and glucose and insulin dynamics in response to exercise, training and aleurone supplementation. At the same time, she participated in practical lessons concerning Physiology and Pathophysiology I and II at the level of the second year of the Bachelor in Veterinary Medicine. Additionally, she presented the work of the Research Group in an international conference in London in 2023.
Academische graad
Doctor in de diergeneeskundige wetenschappen
Taal proefschrift
Prof. dr. Catherine Delesalle UGent - Prof. dr. Elisabeth-Lidwien (E.J.M.M.) Verdegaal, Thermoregulation Research Group, School of Animal and Veterinary Science, University of Adelaide

Korte beschrijving

This PhD is part of a larger equine training project in which the effect of different types of training in different breeds is studied. The primary focus of the current PhD work is threefold: (1) comparing baseline muscular physiology between three different archetype equine breeds; (2) studying the role of carbohydrates to fuel exercise in horses; and (3) exploring strategies to modulate the glucose/insulin metabolism in horses in untrained condition. Chapter 1: The introductory section of this PhD thesis provides an in-depth overview of the current state of the art knowledge about equine muscle physiology, also involving other animal species and humans from a comparative perspective. This section furnishes readers with essential knowledge to better understand the rationale behind the executed studies and the applied study set-ups. It encompasses a detailed overview of the general architecture of muscles and how this is linked to their function. Information is provided about key morpho-physiological parameters involved in the current PhD, such as fiber specific cross-sectional area (fCSA) and mean fiber cross sectional area (mfCSA), muscle fiber type composition and metabolic analyses. Since the second study also involves training, different types of training are being highlighted, at least the three archetype different training protocols: endurance training, power training and interval training. Also, the concept of Standardized Exercise Tests (SETs) is being explained in this section, since these SETs are essential for proper and objective follow-up of effect of training on performance capacity. Finally, the concept of muscle plasticity or how the muscle adapts itself in answer to different types of stimuli is being discussed.


Donderdag 18 april 2024, 17:00
kliniekauditorium A, Salisburylaan 133, 9820 Merelbeke

If you would like to attend, please register before 1st of April 2024 by email to Carmen.VidalMorenodeVega@UGent.be.